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HMG CoA reductase inhibitors (statins) for preventing acute kidney injury after surgical procedures requiring cardiac bypass

  1. Michelle Lewicki1,*,
  2. Irene Ng2,
  3. Antoine G Schneider1

Editorial Group: Cochrane Renal Group

Published Online: 30 APR 2013

DOI: 10.1002/14651858.CD010480


How to Cite

Lewicki M, Ng I, Schneider AG. HMG CoA reductase inhibitors (statins) for preventing acute kidney injury after surgical procedures requiring cardiac bypass (Protocol). Cochrane Database of Systematic Reviews 2013, Issue 4. Art. No.: CD010480. DOI: 10.1002/14651858.CD010480.

Author Information

  1. 1

    Monash University, Department of Epidemiology and Preventive Medicine, Melbourne, VIC, Australia

  2. 2

    Royal Melbourne Hospital, Department of Anaesthesia and Pain Management, Parkville, VIC, Australia

*Michelle Lewicki, Department of Epidemiology and Preventive Medicine, Monash University, Melbourne, VIC, Australia. michellelewicki@me.com.

Publication History

  1. Publication Status: New
  2. Published Online: 30 APR 2013

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Abstract

  1. Top of page
  2. Abstract

This is the protocol for a review and there is no abstract. The objectives are as follows:

This review aims to look at the evidence that supports the benefits of perioperative statins in prevention of AKI occurring in hospitalised adults after surgery requiring cardiac bypass. The main objectives are:

  1. To determine whether statin use is associated with the prevention of development of AKI.
  2. To determine whether the use of statins is associated with a reduction in in-hospital mortality.
  3. To determine whether the use of statins is associated with a reduction in the need for renal replacement therapy.
  4. To determine any adverse effects associated with the use of statins.