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Intervention Review

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Antiepileptic drugs for the treatment of severe myoclonic epilepsy in infancy

  1. Francesco Brigo1,*,
  2. Monica Storti2

Editorial Group: Cochrane Epilepsy Group

Published Online: 19 NOV 2013

Assessed as up-to-date: 15 MAY 2013

DOI: 10.1002/14651858.CD010483.pub2


How to Cite

Brigo F, Storti M. Antiepileptic drugs for the treatment of severe myoclonic epilepsy in infancy. Cochrane Database of Systematic Reviews 2013, Issue 11. Art. No.: CD010483. DOI: 10.1002/14651858.CD010483.pub2.

Author Information

  1. 1

    University of Verona, Department of Neurological, Neuropsychological, Morphological and Movement Sciences. Section of Clinical Neurology, Verona, Italy

  2. 2

    University of Verona, Department of Medicine, Verona, Italy

*Francesco Brigo, Department of Neurological, Neuropsychological, Morphological and Movement Sciences. Section of Clinical Neurology, University of Verona, P.le L.A. Scuro, 10, Verona, 37134, Italy. dr.francescobrigo@gmail.com.

Publication History

  1. Publication Status: New
  2. Published Online: 19 NOV 2013

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This is not the most recent version of the article. View current version (18 MAY 2017)

References

References to studies included in this review

  1. References to studies included in this review
  2. References to studies excluded from this review
  3. Additional references
  4. References to other published versions of this review
Chiron 2000 {published data only}
  • Chiron C, Marchand MC, Tran A, Rey E, d'Athis P, Vincent J, et al. Stiripentol in severe myoclonic epilepsy in infancy: a randomised placebo-controlled syndrome-dedicated trial. STICLO Study Group. Lancet 2000;356(9242):1638-42.
Guerrini 2002 {published data only}
  • Guerrini R, Tonnelier S, d´Athis P, Rey E, Vincent J, Pons G. Stiripentol in severe myoclonic epilepsy in infancy (SMEI): a placebo-controlled Italian trial. Epilepsia 2002;43(Suppl 8):155.

References to studies excluded from this review

  1. References to studies included in this review
  2. References to studies excluded from this review
  3. Additional references
  4. References to other published versions of this review
Chiron 1999a {published data only}
  • Chiron C, Marchand MC, d'Athis P, Rey E, Vincent J, Dulac O, et al. Stiripentol in severe myoclonic epilepsy in infancy (SMEI): a placebo-controlled trial [abstract]. Epilepsia 1999;40(Suppl 2):180.
Chiron 1999b {published data only}
  • Chiron C, Marchand MC, d'Athis P, Rey E, Vincent J, Pons G, et al. Stiripentol in severe myoclonic epilepsy in infancy (SMEI): a placebo-controlled trial [abstract]. Epilepsia 1999;40(Suppl 7):159.
Coppola 2002 {published data only}
  • Coppola G, Capovilla G, Montagnini A, Romeo A, Spano M, Tortorella G, et al. Topiramate as add-on drug in severe myoclonic epilepsy in infancy: an Italian multicenter open trial. Epilepsy Research 2002;49(1):45-8.
JPRN-JapicCTI-101116 2010 {published data only}
  • JPRN-JapicCTI-101116. Open phase III study of ME2080 in patients with Dravet syndrome, 2010. http://www.clinicaltrials.jp/user/showCteDetailE.jsp?japicId=JapicCTI-101116 (accessed 20th May 2013).
JPRN-JMA-IIA00014 2007 {published data only}
  • JPRN-JMA-IIA00014. Clinical evaluation of stiripentol in Dravet syndrome, 2007. https://dbcentre3.jmacct.med.or.jp/jmactr/App/JMACTRE02_04/JMACTRE02_04.aspx?kbn=3&seqno=382 (accessed 20th May 2013).
Kassai 2008 {published data only}
NCT01533506 2012 {published data only}
  • NCT01533506. Compassionate use of stiripentol in intractable epilepsy due to Dravet syndrome, 2012. http://clinicaltrials.gov/show/NCT01533506 (accessed 20th May 2013).
NCT01607073 2012 {published data only}
  • NCT01607073. Verapamil as adjunctive seizure therapy for children and young adults with Dravet syndrome, 2012. http://clinicaltrials.gov/show/NCT01607073 (accessed 20th May 2013).
Nguyen Thanh 2002 {published data only}
  • Nguyen Thanh T, Chiron C, Dellatolas G, Rey E, Pons G, Vincent J, et al. Long term efficacy and tolerance of stiripentol in severe myoclonic epilepsy of infancy (Dravet's syndrome). Archives de Pediatrie 2002;9(11):1120-7.
Oguni 1994 {published data only}
Striano 2007 {published data only}
Thanh 2002 {published data only}
  • ThanhTN, Chiron C, Dellatolas G, Rey E, Pons G, Vincent J, et al. Long-term efficacy and tolerance of stiripentol in severe myoclonic epilepsy of infancy (Dravet's syndrome). Archives de Pediatrie 2002;9(11):1120-7.

Additional references

  1. References to studies included in this review
  2. References to studies excluded from this review
  3. Additional references
  4. References to other published versions of this review
Chiron 2005
Chiron 2007
Chiron 2013
Dravet 2005
  • Dravet C, Bureau M, Oguni H, Fukuyama Y, Cokar O. Severe myoclonic epilepsy in infancy: Dravet syndrome. Advances in Neurology 2005;95:71-102.
Fisher 2009
Fujiwara 2003
  • Fujiwara T, Sugawara T, Mazaki-Miyazaki E, Takahashi Y, Fukushima K, Watanabe M, et al. Mutations of sodium channel alpha subunit type 1(SCN1A) in intractable childhood epilepsies with frequent generalized tonic–clonic seizures. Brain 2003;126:531–46.
Giraud 2006
  • Giraud C, Treluyer JM, Rey E, Chiron C, Vincent J, Pons G, et al. In vitro and in vivo inhibitory effect of stiripentol on clobazam metabolism. Drug Metabolism and Disposition 2006;34:608-11.
Higgins 2003
Higgins 2011
  • Higgins JPT, Green S (editors). Cochrane Handbook for Systematic Reviews of Interventions Version 5.1.0 [updated March 2011]. The Cochrane Collaboration, 2011.
Hurst 1990
ILAE 1989
  • Commission on Classification and Terminology of the International League Against Epilepsy. Proposal for revised classification of epilepsies and epileptic syndromes. Epilepsia 1989;30:289-99.
Kirkham 2010
  • Kirkham JJ, Dwan KM, Altman DG, Gamble C, Dodd S, Smyth R, Williamson PR. impact of outcome reporting bias in randomised controlled trials on a cohort of systematic reviews. BMJ 2010;340:c356.
Kwan 2010
Lefebvre 2011
  • Lefebvre C, Manheimer E, Glanville J. Chapter 6: Searching for studies. In: Higgins JPT, Green S (editors). Cochrane Handbook for Systematic Reviews of Interventions Version 5.1.0 [updated March 2011]. The Cochrane Collaboration, 2011. www.cochrane-handbook.org.
Nabbout 2003
Perez 1999
Quilichini 2006
Yakoub 1992

References to other published versions of this review

  1. References to studies included in this review
  2. References to studies excluded from this review
  3. Additional references
  4. References to other published versions of this review
Brigo 2013
  • Brigo F, Storti M, Del Felice A. Antiepileptic drugs for the treatment of severe myoclonic epilepsy in infancy. Cochrane Database of Systematic Reviews 2013, Issue 4. [DOI: 10.1002/14651858.CD010483]