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Intervention Protocol

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Splenectomy for people with thalassaemia major and intermedia

  1. Manu Easow Mathew1,*,
  2. Akshay Sharma2,
  3. Shabin Fahad3,
  4. Rajeev Aravindakshan4

Editorial Group: Cochrane Cystic Fibrosis and Genetic Disorders Group

Published Online: 31 MAY 2013

Assessed as up-to-date: 17 APR 2013

DOI: 10.1002/14651858.CD010517


How to Cite

Easow Mathew M, Sharma A, Fahad S, Aravindakshan R. Splenectomy for people with thalassaemia major and intermedia (Protocol). Cochrane Database of Systematic Reviews 2013, Issue 5. Art. No.: CD010517. DOI: 10.1002/14651858.CD010517.

Author Information

  1. 1

    Christian Medical College, South Asian Cochrane Centre and Network, Vellore, Tamil Nadu, India

  2. 2

    University of Kentucky, Department of Pediatrics, Lexington, Kentucky, USA

  3. 3

    Kasturba Medical College, Department of Forensic Medicine, Mangalore, Karnataka, India

  4. 4

    Pushpagiri Institute of Medical Sciences and Research Centre, Department of Community Medicine, Pathanamthitta, Kerala, India

*Manu Easow Mathew, South Asian Cochrane Centre and Network, Christian Medical College, Carman Block, Bagayam Campus, Vellore, Tamil Nadu, 632002, India. manu56@gmail.com.

Publication History

  1. Publication Status: New
  2. Published Online: 31 MAY 2013

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References

Additional references

Aydinok 2011
  • Aydinok Y, Bayraktaroglu S, Yildiz D, Alper H. Myocardial iron loading in patients with thalassemia major in Turkey and the potential role of splenectomy in myocardial siderosis. Journal of Pediatric Hematology/Oncology 2011;33(5):374-8. [PUBMED: 21364469]
Belhoul 2012
  • Belhoul KM,  Bakir ML,  Saned MS,  Kadhim AM,  Musallam KM,  Taher AT. Serum ferritin levels and endocrinopathy in medically treated patients with β thalassemia major. Annals of Hematology 2012;91(7):1107-14.
Cao 2010
Colah 2010
  • Colah R, Gorakshakar A, Nadkarni A. Global burden, distribution and prevention of β-thalassemias and hemoglobin E disorders. Expert Review of Hematology 2010;3(1):103-17. [PUBMED: 21082937]
Cooley 1925
  • Cooley TB, Lee P. A series of cases of splenomegaly in children with anemia and peculiar bone changes. Transactions of the American Pediatric Society 1925;37:29–30.
Eldor 2002
Galanello 2010
Gaziev 2011
Guyton 2011
  • Hall JE. Guyton and Hall Textbook of Medical Physiology. 12th Edition. New Delhi: Elsevier, 2001.
Harvey 2010
  • Harvey RA, Ferrier DR. Lippincott's Illustrated Reviews: Biochemistry. 5th Edition. Wolters Kluwer, 2010.
Higgins 2011a
  • Higgins JPT, Altman DG. Chapter 8: Assessing risk of bias in included studies. In: Higgins JPT, Green S (editors). Cochrane Handbook for Systematic Reviews of Interventions Version 5.1.0 [updated March 2011]. The Cochrane Collaboration, 2011. Available from www.cochrane-handbook.org 2011.
Higgins 2011b
  • Higgins JPT, Deeks JJ, Altman DG, on behalf of the CSMG. Chapter 16: Special topics in statistics. In: Higgins JPT, Green S (editors). Cochrane Handbook of Systematic Reviews of Interventions. Version 5.1 [updated March 2011]. The Cochrane Collaboration, 2011. Available from www.cochrane-handbook.org.
Higgins 2011c
  • Sterne JAC, Egger M, Moher D, on behalf of the CSMG. Chapter 10: Addressing reporting biases. In: Higgins JPT, Green S (editors). Cochrane Handbook of Systematic Reviews of Interventions. Version 5.1 [updated March 2011]. The Cochrane Collaboration, 2011. Available from www.cochrane-handbook.org.
Hollenberg 1988
  • Hollenberg JP, Subak LL, Ferry JJ Jr, Bussel JB. Cost-effectiveness of splenectomy versus intravenous gamma globulin in treatment of chronic immune thrombocytopenic purpura in childhood. Journal of Pediatrics 1988;112(4):530-9. [PUBMED: 2450983]
Lichtman 2005
  • Lichtman MAI, Beutler E, Kaushansky K, Kipps TJ, Seligsohn U, Prchal J. Williams Hematology. 7th Edition. McGraw-Hill Professional, 2005.
Medtour 2012
  • Medical Tourism Corporation. Splenectomy Abroad. www.medicaltourismco.com/general-surgery/splenectomy-surgery-abroad.php (accessed 02 March 2012).
Modell 2008
  • Modell B, Khan M, Darlison M, Westwood MA, Ingram D, Pennell DJ. Improved survival of thalassaemia major in the UK and relation to T2* cardiovascular magnetic resonance. Journal of Cardiovascular Magnetic Resonance 2008;10(1):42.
Morsy 2008
  • Morsy MF, Alnajjar AA, Almuzainy IS, Alhawsawi ZM, Alserafi MH, Ahmed AA. Splenectomized versus non-splenectomized patients with thalassemia major. Echocardiographic comparison. Saudi Medical Journal 2008;29(9):1310-4. [PUBMED: 18813418]
Piga 2011
Prati 2000
Rasekhi 2009
  • Rasekhi AR, Naderifar M, Bagheri MH, Shahriari M, Foroutan H, Karimi M, et al. Radiofrequency ablation of the spleen in patients with thalassemia intermedia: a pilot study. British Journal of Surgery 2011;98(6):751-60. [PUBMED: 19380572]
RevMan 2011 [Computer program]
  • The Nordic Cochrane Centre, The Cochrane Collaboration. Review Manager (RevMan). Version 5.1. Copenhagen: The Nordic Cochrane Centre, The Cochrane Collaboration, 2011.
Saad 2011
Sabiston 2004
  • Townsend CM, Beauchamp RD, Evers BM, Mattox KL. Sabiston Textbook of Surgery. 17th Edition. Vol. 2, New Delhi, India: Elsevier, 2004.
Singer 2006
Smith 1960
Taher 2006a
Taher 2006b
  • Taher A, Isma'eel H, Mehio G, Bignamini D, Kattamis A, Rachmilewitz EA, et al. Prevalence of thromboembolic events among 8,860 patients with thalassaemia major and intermedia in the Mediterranean area and Iran. Thrombosis and Haemostasis 2006;96(4):488-91. [PUBMED: 17003927]
Taher 2011
Telfer 2009
  • Telfer PT, Warburton F, Christou S, Hadjigavriel M, Sitarou M, Kolnagou A, et al. Improved survival in thalassemia major patients on switching from desferrioxamine to combined chelation therapy with desferrioxamine and deferiprone. Haematologica 2009;94(12):1777–8.
Tripodi 2009
  • Tripodi A, Cappellini MD, Chantarangkul V, Padovan L, Fasulo MR, Marcon A, et al. Hypercoagulability in splenectomized thalassemic patients detected by whole-blood thromboelastometry, but not by thrombin generation in platelet-poor plasma. Haematologica 2009;94(11):1520-7. [PUBMED: 19648162]
Vichinsky 2005
Zarina 2010
  • Zarina AL, Norazlin KN, Hamidah A, Aziz DA, Zulkifli SZ, Jamal R. Spectrum of infections in splenectomised thalassaemia patients. Medical Journal of Malaysia 2011;65(4):283-5. [PUBMED: 21901946]