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Primary prophylaxis for venous thromboembolism in people undergoing major amputation of the lower extremity

  1. Lindsay Robertson1,*,
  2. Aidan Roche2

Editorial Group: Cochrane Peripheral Vascular Diseases Group

Published Online: 16 DEC 2013

Assessed as up-to-date: 8 MAY 2013

DOI: 10.1002/14651858.CD010525.pub2


How to Cite

Robertson L, Roche A. Primary prophylaxis for venous thromboembolism in people undergoing major amputation of the lower extremity. Cochrane Database of Systematic Reviews 2013, Issue 12. Art. No.: CD010525. DOI: 10.1002/14651858.CD010525.pub2.

Author Information

  1. 1

    The Freeman Hospital, Department of Vascular Surgery, Newcastle upon Tyne, UK

  2. 2

    University of Newcastle, Newcastle Upon Tyne, UK

*Lindsay Robertson, Department of Vascular Surgery, The Freeman Hospital, Newcastle upon Tyne Hospitals NHS Foundation Trust, High Heaton, Newcastle upon Tyne, NE7 7DN, UK. lindsay.robertson@nuth.nhs.uk. lindsay.robertson@ed.ac.uk.

Publication History

  1. Publication Status: New
  2. Published Online: 16 DEC 2013

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References

References to studies included in this review

  1. References to studies included in this review
  2. References to studies excluded from this review
  3. Additional references
Lastória 2006 {published data only}
  • Lastória S, Rollo HA, Yoshida WB, Giannini M, Moura R, Maffei FHA. Prophylaxis of deep-vein thrombosis after lower extremity amputation: comparison of low molecular weight heparin with unfractionated heparin. Acta Cirúrgica Brasileira 2006;21(3):184-6.
Williams 1978 {published data only}
  • Williams JW, Eikman EA, Greenberg SH, Hewitt JC, Lopez-Cuenca E, Jones GP, et al. Failure of low dose heparin to prevent pulmonary embolism after hip surgery or above the knee amputation. Annals of Surgery 1978;188(4):468-74.

References to studies excluded from this review

  1. References to studies included in this review
  2. References to studies excluded from this review
  3. Additional references
Atkins 1978 {published data only}
  • Atkins P, Brown IK, Downie RJ, Haggart BG, Littler J, Robb PM, et al. The value of phenformin and ethyloestrenol in the prevention of deep venous thrombosis in patients undergoing surgery. Thrombosis and Haemostasis 1978;39(1):89-96.
Covey 1975 {published data only}
  • Covey TH, Sherman L, Baue AE. Low-dose heparin in postoperative patients: a prospective, coded study. Archives of Surgery 1975;110(8):1021-6.
Di Serio 1985 {published data only}
  • Di Serio FJ, Sasahara AA. United States trial of dihydroergotamine and heparin prophylaxis of deep vein thrombosis. American Journal of Surgery 1985;150(4A):25-32.
Haas 2005 {published data only}
  • Haas S, Wolf H, Kakkar AK, Fareed J, Encke A. Prevention of fatal pulmonary embolism and mortality in surgical patients: a randomised double-blind comparison of LMWH with unfractionated heparin. Thrombosis and Haemostasis 2005;94(4):814-9.
Huttenen 1977 {published data only}
  • Huttunen H, Mattila MA, Alhava EM, Kettunen K, Karjalainen P, Poikolainen P, et al. Peroperative infusion of dextran 70 and dextran 40 in the prevention of postoperative deep venous thrombosis as confirmed by the I-125-labelled fibrinogen uptake method. Annales Chirurgiae et Gynaecologiae 1977;66(2):79-81.
Kakkar 1978 {published data only}
  • Kakkar VV, Lawrence D, Bentley PG, De Haas HA, Ward VP, Scully MF. A comparative study of low doses of heparin and a heparin analogue in the prevention of postoperative deep vein thrombosis. Thrombosis Research 1978;13(1):111-22.
Kakkar 2005 {published data only}
  • Kakkar AK, Haas S, Wolf H, Encke A. Evaluation of perioperative fatal pulmonary embolism and death in cancer surgical patients: the MC-4 cancer substudy. Thrombosis and Haemostasis 2005;94(4):867-71.
Kill 1979 {published data only}
  • Kiil J, Møoller JC. Postoperative deep vein thrombosis of the lower limb and prophylactic value of heparin evaluated by phlebography. Acta Radiologica: Diagnosis 1979;20(3):507-12.
Mantz 2011 {published data only}
  • Mantz J, Samama CM, Tubach F, Devereaux PJ, Collet JP, Albaladejo P, et al. for the Stratagem Study Group. Impact of preoperative maintenance or interruption of aspirin on thrombotic and bleeding events after elective non-cardiac surgery: the multicentre, randomized, blinded, placebo-controlled, STRATAGEM trial. British Journal of Anaesthesia 2011;107(6):899-910.
Nicolaides 1972 {published data only}
  • Nicolaides AN, Dupont PA, Desai S, Lewis JD, Douglas JN, Dodsworth H, et al. Small doses of subcutaneous sodium heparin in preventing deep venous thrombosis after major surgery. Lancet 1972;2(7783):890-3.
Pachter 1977 {published data only}
Strand 1975 {published data only}
  • Strand L, Bank-Mikkelsen OK, Lindewald H. Small heparin doses as prophylaxis against deep-vein thrombosis in major surgery. Acta Chirurgica Scandinavica 1975;141(7):624-7.

Additional references

  1. References to studies included in this review
  2. References to studies excluded from this review
  3. Additional references
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Bandeira 2008
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Burke 2000
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