Intervention Protocol

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Prehospital versus in-hospital initiation of mild therapeutic hypothermia for survival and neuroprotection after out-of-hospital cardiac arrest

  1. Jasmin Arrich*,
  2. Christof Havel,
  3. Michael Holzer,
  4. Harald Herkner

Editorial Group: Cochrane Anaesthesia Group

Published Online: 6 JUN 2013

DOI: 10.1002/14651858.CD010570


How to Cite

Arrich J, Havel C, Holzer M, Herkner H. Prehospital versus in-hospital initiation of mild therapeutic hypothermia for survival and neuroprotection after out-of-hospital cardiac arrest (Protocol). Cochrane Database of Systematic Reviews 2013, Issue 6. Art. No.: CD010570. DOI: 10.1002/14651858.CD010570.

Author Information

  1. Medical University of Vienna, Department of Emergency Medicine, Vienna, Austria

*Jasmin Arrich, Department of Emergency Medicine, Medical University of Vienna, Währinger Gürtel 18-20 / 6D, Vienna, 1090, Austria. jasmin.arrich@meduniwien.ac.at.

Publication History

  1. Publication Status: New
  2. Published Online: 6 JUN 2013

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Abstract

  1. Top of page
  2. Abstract

This is the protocol for a review and there is no abstract. The objectives are as follows:

We aim to perform a systematic review and meta-analysis to assess the effectiveness of prehospital initiation of therapeutic hypothermia in comparison to later or in-hospital initiation of therapeutic hypothermia in patients with prehospital cardiac arrest. Our primary outcome measures, among other patient-relevant variables, are survival and neurologic outcome. We plan to undertake subgroup analyses according to the mode of therapeutic hypothermia and the cardiac arrest situation, and sensitivity analyses to assess the robustness of our estimates.