Pancreatic duct guidewire placement for biliary cannulation for the prevention of post-endoscopic retrograde cholangiopancreatography (ERCP)

  • Protocol
  • Intervention

Authors


Abstract

This is the protocol for a review and there is no abstract. The objectives are as follows:

To assess the clinical effectiveness of the pancreatic duct guidewire (PGW) technique in difficult CBD cannulation for the prevention of PEP by systematic review and meta-analysis of RCTs.

The objectives of this review are two-fold:

  1. to assess whether the PGW technique shows any overall benefit in reducing adverse clinical outcomes, including PEP and other ERCP-related complications (bleeding, perforation, cholangitis, mortality), compared to: (a) persistent attempts with conventional cannulation techniques (contrast- or guidewire-assisted cannulation and/or (b) other advanced techniques (e.g. precut sphincterotomy, pancreatic duct stent placement, endoscopic ultrasound rendezvous technique) in difficult biliary cannulation; and

  2. to assess whether the technical success of CBD cannulation can be improved by the PGW technique compared to: (a) persistent attempts with conventional cannulation techniques (contrast- or guidewire-assisted cannulation) and/or (b) advanced techniques (e.g. precut sphincterotomy, pancreatic duct stent placement, endoscopic ultrasound rendezvous) in difficult biliary cannulation.