Intervention Review

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Behavioral interventions for improving condom use for dual protection

  1. Laureen M Lopez1,*,
  2. Conrad Otterness2,
  3. Mario Chen3,
  4. Markus Steiner1,
  5. Maria F Gallo4

Editorial Group: Cochrane Fertility Regulation Group

Published Online: 26 OCT 2013

Assessed as up-to-date: 2 OCT 2013

DOI: 10.1002/14651858.CD010662.pub2

How to Cite

Lopez LM, Otterness C, Chen M, Steiner M, Gallo MF. Behavioral interventions for improving condom use for dual protection. Cochrane Database of Systematic Reviews 2013, Issue 10. Art. No.: CD010662. DOI: 10.1002/14651858.CD010662.pub2.

Author Information

  1. 1

    FHI 360, Clinical Sciences, Research Triangle Park, North Carolina, USA

  2. 2

    Global Health Access Program, Mae Sot, Tak, Thailand

  3. 3

    FHI 360, Division of Biostatistics, Research Triangle Park, North Carolina, USA

  4. 4

    The Ohio State University, Division of Epidemiology, Columbus, Ohio, USA

*Laureen M Lopez, Clinical Sciences, FHI 360, P.O. Box 13950, Research Triangle Park, North Carolina, 27709, USA.

Publication History

  1. Publication Status: New
  2. Published Online: 26 OCT 2013



References to studies included in this review

  1. References to studies included in this review
  2. References to studies excluded from this review
  3. Additional references
Boyer 2005 {published and unpublished data}
  • Boyer CB, Shafer MA, Shaffer RA, Brodine SK, Pollack LM, Betsinger K, et al. Evaluation of a cognitive-behavioral, group, randomized controlled intervention trial to prevent sexually transmitted infections and unintended pregnancies in young women. Preventive Medicine 2005;40(4):420-31.
Cowan 2010 {published data only}
  • Cowan F M, Pascoe S J, Langhaug L F, Dirawo J, Chidiya S, Jaffar S, et al. The Regai Dzive Shiri Project: a cluster randomised controlled trial to determine the effectiveness of a multi-component community-based HIV prevention intervention for rural youth in Zimbabwe--study design and baseline results. Tropical Medicine & International Health 2008;13(10):1235-44.
  • Cowan F M, Pascoe S J, Langhaug L F, Mavhu W, Chidiya S, Jaffar S, et al. The Regai Dzive Shiri project: results of a randomized trial of an HIV prevention intervention for youth. AIDS 2010;24(16):2541-52.
  • Hayes RJ, Changaluchab J, Ross DA, Gavyolec A, Todd J, Obasi AIN, et al. The MEMA kwa Vijana Project: Design of a community randomised trial of an innovative adolescent sexual health intervention in rural Tanzania. Contemporary Clinical Trials 2005;26(4):430-42.
  • Obasi AI, Cleophas B, Ross DA, Chima KL, Mmassy G, Gavyole A, et al. Rationale and design of the MEMA kwa Vijana adolescent sexual and reproductive health intervention in Mwanza Region, Tanzania. AIDS Care 2006;18(4):311-22.
Jewkes 2008 {published data only}
  • Jewkes R, Nduna M, Levin J, Jama N, Dunkle K, Khuzwayo N, et al. A cluster randomized-controlled trial to determine the effectiveness of Stepping Stones in preventing HIV infections and promoting safer sexual behaviour amongst youth in the rural Eastern Cape, South Africa: trial design, methods and baseline findings. Tropical Medicine & International Health. 2006/01/10 2006; Vol. 11, issue 1:3-16.
  • Jewkes R, Nduna M, Levin J, Jama N, Dunkle K, Puren A, et al. Impact of stepping stones on incidence of HIV and HSV-2 and sexual behaviour in rural South Africa: cluster randomised controlled trial. BMJ. 2008/08/09 2008; Vol. 337:a506. [: NCT00332878]
Kamali 2003 {published data only}
  • Kamali A, Kinsman J, Nalweyiso N, Mitchell K, Kanyesigye E, Kengeya-Kayondo J F, et al. A community randomized controlled trial to investigate impact of improved STD management and behavioural interventions on HIV incidence in rural Masaka, Uganda: trial design, methods and baseline findings. Tropical Medicine & International Health 2002;7(12):1053-63.
  • Kamali A, Quigley M, Nakiyingi J, Kinsman J, Kengeya-Kayondo J, Gopal R, et al. Syndromic management of sexually-transmitted infections and behaviour change interventions on transmission of HIV-1 in rural Uganda: a community randomised trial. Lancet 2003;361(9358):645-52.
Petersen 2007 {published and unpublished data}
Ross 2007 {published data only}
  • Doyle A M, Ross D A, Maganja K, Baisley K, Masesa C, Andreasen A, et al. Long-term biological and behavioural impact of an adolescent sexual health intervention in Tanzania: follow-up survey of the community-based MEMA kwa Vijana Trial. PLoS Med 2010;7(6):e1000287.
  • Hayes RJ, Changaluchab J, Ross DA, Gavyolec A, Todd J, Obasi AIN, et al. The MEMA kwa Vijana Project: Design of a community randomised trial of an innovative adolescent sexual health intervention in rural Tanzania. Contemporary Clinical Trials 2005;26(4):430-42.
  • Obasi AI, Cleophas B, Ross DA, Chima KL, Mmassy G, Gavyole A, et al. Rationale and design of the MEMA kwa Vijana adolescent sexual and reproductive health intervention in Mwanza Region, Tanzania. AIDS Care 2006;18(4):311-22.
  • Ross DA, Changaluchab J, Obasia AIN, Todd J, Plummer ML, Cleophas-Mazige B, et al. Biological and behavioural impact of an adolescent sexual health intervention in Tanzania: a community-randomized trial. AIDS 2007;21(14):1943-55.
Stephenson 2008 {published data only}
  • Stephenson J, Strange V, Allen E, Copas A, Johnson A, Bonell C, et al. The long-term effects of a peer-led sex education programme (RIPPLE): a cluster randomised trial in schools in England. PLoS Medicine 2008;5(11):1579-90.
  • Stephenson JM, Oakley A, Johnson AM, Forrest S, Strange V, Charleston S, et al. A school-based randomized controlled trial of peer-led sex education in England. Controlled Clinical Trials 2003;24(5):643-57.
  • Stephenson JM, Strange V, Forrest S, Oakley A, Copas A, Allen E, et al. Pupil-led sex education in England (RIPPLE study): cluster-randomised intervention trial. Lancet 2004;364(9431):338-46.

References to studies excluded from this review

  1. References to studies included in this review
  2. References to studies excluded from this review
  3. Additional references
Allen 1992 {published data only}
  • Allen S, Serufilira A, Bogaerts J, Van de Perre P, Nsengumuremyi F, Lindan C, et al. Confidential HIV testing and condom promotion in Africa. Impact on HIV and gonorrhea rates. JAMA. 1992/12/16 1992; Vol. 268, issue 23:3338-43.
  • Allen S, Serufilira A, Gruber V, Kegeles S, Van de Perre P, Carael M, et al. Pregnancy and contraception use among urban Rwandan women after HIV testing and counseling. American Journal of Public Health. 1993/05/01 1993; Vol. 83, issue 5:705-10.
  • Allen S, Tice J, Perre P, Serufilira A, Hudes E, Nsengumuremyi F, et al. Effect of serotesting with counselling on condom use and seroconversion among HIV discordant couples in Africa. BMJ 1992; Vol. 304, issue 6842:1605-9.
Allen 2003 {published data only}
  • Allen S, Meinzen-Derr J, Kautzman M, Zulu I, Trask S, Fideli U, et al. Sexual behavior of HIV discordant couples after HIV counseling and testing. AIDS 2003; Vol. 17, issue 5:733-40.
Bachanas 2013 {published data only (unpublished sought but not used)}
  • Bachanas P. HIV Prevention for PLHIV: Evaluation of an Intervention Toolkit for HIV Care & Treatment Settings. (accessed 31 Jul 2012).
  • Kidder DP, Bachanas P, Medley A, Pals S, Nuwagaba-Biribonwoha H, Ackers M, et al. HIV prevention in care and treatment settings: baseline risk behaviors among HIV patients in Kenya, Namibia, and Tanzania. PloS one. 2013/03/06 2013; Vol. 8, issue 2:e57215.
Barnet 2009 {published data only}
  • Barnet B, Liu J, DeVoe M, Duggan AK, Gold MA, Pecukonis E. Motivational intervention to reduce rapid subsequent births to adolescent mothers: a community-based randomized trial. Annals of Family Medicine 2009, issue 5:436-45.
Black 2006 {published data only (unpublished sought but not used)}
  • Black MM, Bentley ME, Papas MA, Oberlander S, Teti LO, McNary S, et al. Delaying second births among adolescent mothers: a randomized, controlled trial of a home-based mentoring program. Pediatrics 2006;118(4):e1087-99.
  • Black MM, Siegel EH, Abel Y, Bentley ME. Home and videotape intervention delays early complementary feeding among adolescent mothers. Pediatrics 2001;107(5):e67.
Boyer 1997 {published data only}
  • Boyer CB, Barrett DC, Peterman TA, Bolan G. Sexually transmitted disease (STD) and HIV risk in heterosexual adults attending a public STD clinic: evaluation of a randomized controlled behavioral risk-reduction intervention trial. AIDS. 1997/03/01 1997; Vol. 11, issue 3:359-67.
Branson 1998 {published data only}
  • Branson BM, Peterman TA, Cannon RO, Ransom R, Zaidi AA. Group counseling to prevent sexually transmitted disease and HIV: a randomized controlled trial. Sexually Transmitted Diseases. 1998/12/19 1998; Vol. 25, issue 10:553-60.
Brou 2009 {published and unpublished data}
  • Brou H, Djohan G, Becquet R, Allou G, Ekouevi DK, Zanou B, et al. Sexual prevention of HIV within the couple after prenatal HIV-testing in West Africa. AIDS Care. 2008/05/02 2008; Vol. 20, issue 4:413-8.
  • Brou H, Viho I, Djohan G, Ekouevi D K, Zanou B, Leroy V, et al. [Contraceptive use and incidence of pregnancy among women after HIV testing in Abidjan, Ivory Coast]. Revue d'epidemiologie et de sante publique 2009;57(2):77-86.
Chacko 2010 {published data only}
  • Chacko M R, Wiemann C M, Kozinetz C A, von Sternberg K, Velasquez M M, Smith P B, et al. Efficacy of a motivational behavioral intervention to promote chlamydia and gonorrhea screening in young women: a randomized controlled trial. J Adolesc Health 2010;46(2):152-61.
De Fine Olivarius 1992 {published data only}
  • De Fine Olivarius F, Worm AM, Petersen CS, Kroon S, Lynge E. Sexual behaviour of women attending an inner-city STD clinic before and after a general campaign for safer sex in Denmark. Genitourinary Medicine 1992; Vol. 68, issue 5:296-9.
Ethier 2011 {published data only}
  • Ethier K A, Dittus P J, DeRosa C J, Chung E Q, Martinez E, Kerndt P R. School-based health center access, reproductive health care, and contraceptive use among sexually experienced high school students. Journal of Adolescent Health 2011;48(6):562-5.
Exner 2011 {published data only}
  • Exner TM, Mantell JE, Hoffman S, Adams-Skinner J, Stein ZA, Leu CS. Project REACH: a provider-delivered dual protection intervention for women using family planning services in New York City. AIDS Care. 2011/01/29 2011; Vol. 23, issue 4:467-75.
Feldblum 2007 {published data only}
  • Feldblum P J, Nasution M D, Hoke T H, Van Damme K, Turner A N, Gmach R, et al. Pregnancy among sex workers participating in a condom intervention trial highlights the need for dual protection. Contraception 2007;76(2):105-10.
Fitzgerald 1999 {published data only}
  • Fitzgerald AM, Stanton BF, Terreri N, Shipena H, Li X, Kahihuata J, et al. Use of Western-based HIV risk-reduction interventions targeting adolescents in an African setting. Journal of Adolescent Health. 1999/07/27 1999; Vol. 25, issue 1:52-61.
  • Stanton BF, Li X, Kahihuata J, Fitzgerald AM, Neumbo S, Kanduuombe G, et al. Increased protected sex and abstinence among Namibian youth following a HIV risk-reduction intervention: a randomized, longitudinal study. AIDS. 1999/01/06 1998; Vol. 12, issue 18:2473-80.
Grossman 2012 {published data only (unpublished sought but not used)}
  • Cohen C. Integrating Family Planning Services Into HIV Care and Treatment in Nyanza Province, Kenya. (accessed 31 Jul 2012).
  • Grossman D, Newmann SJ, Onoro M, Blat C, Bukusi EA, Shade S, et al. Effect of integrating family planning services into HIV care and treatment on contraceptive use and pregnancy among women in Nyanza, Kenya. Presented at Integration for Impact: Reproductive Health and HIV Services; 2012 Sep 12; Nairobi, Kenya. (accessed 08 May 2013).
Kershaw 2009 {published data only}
  • Kershaw T S, Magriples U, Westdahl C, Rising S S, Ickovics J. Pregnancy as a window of opportunity for HIV prevention: effects of an HIV intervention delivered within prenatal care. Am J Public Health 2009;99(11):2079-86.
King 1995 {published data only}
  • King R, Estey J, Allen S, Kegeles S. A family planning intervention to reduce vertical transmission of HIV in Rwanda. AIDS. US: Lippincott Williams & Wilkins, 1995; Vol. 9, issue Suppl 1:S45-51.
Kirby 2010 {published data only}
  • Kirby D, Raine T, Thrush G, Yuen C, Sokoloff A, Potter SC. Impact of an intervention to improve contraceptive use through follow-up phone calls to female adolescent clinic patients. Perspectives on Sexual and Reproductive Health 2010;42(4):251-7. [: NCT00230880]
  • Raine TR. Young Woman's Reach Project: Trial of an Intervention to Impact Contraceptive Behavior, Unintended Pregnancy, and Sexually Transmitted Infections (STIs) Among Adolescent Females (REACH). (accessed 10 Dec 2010).
Kosgei 2011 {published and unpublished data}
  • Kosgei RJ, Lubano KM, Shen C, Wools-Kaloustian KK, Musick BS, Siika AM, et al. Impact of integrated family planning and HIV care services on contraceptive use and pregnancy outcomes: a retrospective cohort study. Journal of Acquired Immune Deficiency Syndrome. 2011/10/04 2011; Vol. 58, issue 5:e121-6.
Morrison-Beedy 2013 {published data only}
  • Morrison-Beedy D, Jones S H, Xia Y, Tu X, Crean H F, Carey M P. Reducing sexual risk behavior in adolescent girls: results from a randomized controlled trial. Journal of Adolescent Health 2013;52(3):314-21.
Ngubane 2008 {published data only}
  • Ngubane N, Patel D, Newell ML, Coovadia HM, Rollins N. Messages about dual contraception in areas of high HIV prevalence are not heeded. South African Medical Journal 2008; Vol. 98, issue 3:209-12.
Ngure 2012 {published data only}
  • Heffron R, Were E, Celum C, Mugo N, Ngure K, Kiarie J, et al. A prospective study of contraceptive use among African women in HIV-1 serodiscordant partnerships. Sex Transm Dis. 2010/07/06 2010; Vol. 37, issue 10:621-8.
  • Ngure K, Heffron R, Mugo N R, Celum C, Cohen C R, Odoyo J, et al. Contraceptive method and pregnancy incidence among women in HIV-1-serodiscordant partnerships. AIDS 2012;26(4):513-8.
Orr 1996 {published data only}
Temmerman 1990 {published data only}
  • Temmerman M, Moses S, Kiragu D, Fusallah S. Impact of single session post-partum counselling of HIV infected women on their subsequent reproductive behaviour. AIDS Care. United Kingdom: Taylor & Francis, 1990; Vol. 2, issue 3:247-52.
  • Temmerman M, Plummer FA, Mirza NB, Ndinya-Achola JO, Wamola IA, Nagelkerke N, et al. Infection with HIV as a risk factor for adverse obstetrical outcome. AIDS. 1990/11/01 1990; Vol. 4, issue 11:1087-93.
Wingood 2004 {published data only}
  • Wingood GM, DiClemente RJ, Mikhail I, Lang DL, McCree DH, Davies SL, et al. A randomized controlled trial to reduce HIV transmission risk behaviors and sexually transmitted diseases among women living with HIV: The WiLLOW Program. Journal of Acquired Immune Deficiency Syndrome. 2004/09/24 2004; Vol. 37 Suppl 2:S58-67.

Additional references

  1. References to studies included in this review
  2. References to studies excluded from this review
  3. Additional references
Albert 1995
Balshem 2011
Beksinska 2011
Blank 2012
  • Blank L, Baxter SK, Payne N, Guillaume LR, Squires H. Systematic review and narrative synthesis of the effectiveness of contraceptive service interventions for young people, delivered in health care settings. Health Education Research 2012;27(6):1102-19.
Borrelli 2011
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Brown 2011
  • Brown JL, Hennessy M, Sales JM, DiClemente RJ, Salazar LF, Vanable PA, et al. Multiple method contraception use among African American adolescents in four US cities. Infectious Diseases in Obstetrics and Gynecology 2011;Jul 18(Epub):765917.
Campbell 2012
Carvalho 2011
Cates 2002
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CDC 2010
  • Centers for Disease Control and Prevention. 2010 STD Treatment Guidelines. (accessed 14 Mar 2013).
Chapman 2012
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Chin 2012
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Crosby 2012
Doyle 2012
Eisenberg 2012
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Fonner 2012
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Halpern 2011
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Schulz 2002
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Wariki 2012
Warner 2008
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Warner 2012
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