Intervention Protocol

You have free access to this content

Induction chemotherapy followed by concurrent chemoradiotherapy versus concurrent chemoradiotherapy with or without adjuvant chemotherapy for locally advanced nasopharyngeal carcinoma

  1. Zhi Rui Zhou1,*,
  2. Zhang Yu Zou2,
  3. Jun Xia3,
  4. Song Qu4

Editorial Group: Cochrane ENT Group

Published Online: 1 AUG 2013

DOI: 10.1002/14651858.CD010667


How to Cite

Zhou ZR, Zou ZY, Xia J, Qu S. Induction chemotherapy followed by concurrent chemoradiotherapy versus concurrent chemoradiotherapy with or without adjuvant chemotherapy for locally advanced nasopharyngeal carcinoma (Protocol). Cochrane Database of Systematic Reviews 2013, Issue 8. Art. No.: CD010667. DOI: 10.1002/14651858.CD010667.

Author Information

  1. 1

    Tumor Hospital of Jilin Province, Department of Radiation Oncology, Changchun, Jilin, China

  2. 2

    Union Hospital of Fujian Medical University, Department of Neurology, Fuzhou, China

  3. 3

    Systematic Review Solutions Ltd, Yan Tai, China

  4. 4

    Cancer Hospital of Guangxi Medical University, Department of Radiation Oncology, Nanning, China

*Zhi Rui Zhou, Department of Radiation Oncology, Tumor Hospital of Jilin Province, No.1018, Huguang Road, Changchun, Jilin, 130012, China. zzr3711@163.com.

Publication History

  1. Publication Status: New
  2. Published Online: 1 AUG 2013

SEARCH

References

Additional references

Al-Sarraf 1998
  • Al-Sarraf M, LeBlanc M, Giri PG, Fu KK, Cooper J, Vuong T, et al. Chemoradiotherapy versus radiotherapy in patients with advanced nasopharyngeal cancer: phase III randomized Intergroup study 0099. Journal of Clinical Oncology 1998;16:1310-7.
Baujat 2006
  • Baujat B, Audry W, Bourhis J, Chan ATC, Onat H, Chua DTT, et al. Chemotherapy in locally advanced nasopharyngeal carcinoma: an individual patient data meta-analysis of eight randomized trials and 1753 patients. International Journal of Radiation Oncology, Biology, Physics 2006;64:47-56.
Baujat 2006a
Buell 1974
Chang 2006
Chua 2001
Deeks 2000
  • Deeks J. Issues in the selection for meta-analyses of binary data. Proceedings of the 8th International Cochrane Colloquium; 2000 Oct 25-28th; Cape Town. Cape Town: Cochrane Collaboration, 2000.
Domenge 2000
  • Domenge C, Hill C, Lefebvre JL, De Raucourt D, Rhein B, Wibault P, et al. Randomized trial of neoadjuvant chemotherapy in oropharyngeal carcinoma. French Groupe d'Etude des Tumeurs de la Tete et du Cou (GETTEC). British Journal of Cancer 2000;83(12):1594-8. [PUBMED: 11189100]
Fountzilas 2012
  • Fountzilas G, Ciuleanu E, Bobos M, Kalogera-Fountzila A, Eleftheraki AG, Karayannopoulou G, et al. Induction chemotherapy followed by concomitant radiotherapy and weekly cisplatin versus the same concomitant chemoradiotherapy in patients with nasopharyngeal carcinoma: a randomized phase II study conducted by the Hellenic Cooperative Oncology Group (HeCOG) with biomarker evaluation. Annals of Oncology 2012;23:427-35.
Haddad 2013
  • Haddad R, O'Neill A, Rabinowits G, Tishler R, Khuri F, Adkins D, et al. Induction chemotherapy followed by concurrent chemoradiotherapy (sequential chemoradiotherapy) versus concurrent chemoradiotherapy alone in locally advanced head and neck cancer (PARADIGM): a randomised phase 3 trial. The Lancet Oncology 2013;14:257-64.
Handbook 2011
  • Higgins JPT, Green S (editors). Cochrane Handbook for Systematic Reviews of Interventions Version 5.1.0 [updated March 2011]. The Cochrane Collaboration, 2011. Available from www.cochrane-handbook.org.
Heilmann 2008
  • Heilmann HP, Molls M, Nieder C, Lu JJ, Brady LW. Nasopharyngeal cancer. Radiation Oncology: An Evidence-based Approach. Springer, 2008:17-36.
Hui 2009
  • Hui EP, Ma BB, Leung SF, King AD, Mo F, Kam MK, et al. Randomized phase II trial of concurrent cisplatin-radiotherapy with or without neoadjuvant docetaxel and cisplatin in advanced nasopharyngeal carcinoma. Journal of Clinical Oncology 2009;27:242-9.
James 2010
  • Cox JD, Ang Kie Kian AK. The nasopharynx. Radiation Oncology: Rationale, Technique, Results. Elsevier, 2010:207-23.
Jemal 2011
Kong 2010
  • Kong L, Zhang YW, Hu CS, Guo Y. Neoadjuvant chemotherapy followed by concurrent chemoradiation for locally advanced nasopharyngeal carcinoma. Chinese Journal of Cancer 2010;29:551-5.
Lorch 2011
  • Lorch JH, Goloubeva O, Haddad RI, Cullen K, Sarlis N, Tishler R, et al. Induction chemotherapy with cisplatin and fluorouracil alone or in combination with docetaxel in locally advanced squamous-cell cancer of the head and neck: long-term results of the TAX 324 randomised phase 3 trial. The Lancet Oncology 2011;12:153-9.
NCT01245959
  • Induction chemotherapy in patients with locoregionally advanced nasopharyngeal carcinoma. http://clinicaltrials.gov/ct2/show/NCT01245959. [NCT01245959]
Oh 2003
  • Oh JL, Vokes EE, Kies MS, Mittal BB, Witt ME, Weichselbaum RR, et al. Induction chemotherapy followed by concomitant chemoradiotherapy in the treatment of locoregionally advanced nasopharyngeal cancer. Annals of Oncology 2003;14:564-9.
Pignon 2000
  • Pignon JP, Bourhis J, Domenge C, Designe L. Chemotherapy added to locoregional treatment for head and neck squamous-cell carcinoma: three meta-analyses of updated individual data. MACH-NC Collaborative Group. Meta-Analysis of Chemotherapy on Head and Neck Cancer. Lancet 2000;355:949-55.
Pignon 2009
  • Pignon JP, le Maitre A, Maillard E, Bourhis J. Meta-analysis of chemotherapy in head and neck cancer (MACH-NC): an update on 93 randomised trials and 17,346 patients. Radiotherapy and Oncology 2009;92:4-14.
Pointreau 2009
  • Pointreau Y, Garaud P, Chapet S, Sire C, Tuchais C, Tortochaux J, et al. Randomized trial of induction chemotherapy with cisplatin and 5-fluorouracil with or without docetaxel for larynx preservation. Journal of the National Cancer Institute 2009;101:498-506.
Posner 2007
  • Posner MR, Hershock DM, Blajman CR, Mickiewicz E, Winquist E, Gorbounova V, et al. Cisplatin and fluorouracil alone or with docetaxel in head and neck cancer. New England Journal of Medicine 2007;357:1705-15.
RevMan 2012 [Computer program]
  • The Nordic Cochrane Centre, The Cochrane Collaboration. Review Manager (RevMan). Version 5.2. Copenhagen: The Nordic Cochrane Centre, The Cochrane Collaboration, 2012.
Ruste 2011
  • Ruste SA, Dizon DS, Ramirez F, Sagpao C, Tiangco B, Fragante E. Induction chemotherapy followed by concurrent chemoradiotherapy vs concurrent chemoradiotherapy followed by chemotherapy in the treatment of patients with advanced nasopharyngeal carcinoma. Philippine Journal of Internal Medicine 2011;49:1-7.
Vermorken 2007
  • Vermorken JB, Remenar E, van Herpen C, Gorlia T, Mesia R, Degardin M, et al. Cisplatin, fluorouracil, and docetaxel in unresectable head and neck cancer. New England Journal of Medicine 2007;357:1695-704.
Wee 2005
  • Wee J, Tan EH, Tai BC, Wong HB, Leong SS, Tan T, et al. Randomized trial of radiotherapy versus concurrent chemoradiotherapy followed by adjuvant chemotherapy in patients with American Joint Committee on Cancer/International Union Against Cancer stage III and IV nasopharyngeal cancer of the endemic variety. Journal of Clinical Oncology 2005;23:6730-8.
Wei 2005