Naloxone for reducing mortality and adverse neurological outcomes following acute traumatic brain injury

  • Protocol
  • Intervention

Authors

  • Jin Lei,

    1. Renji Hospital, Shanghai Jiaotong University School of Medicine, Department of Neurosurgery, Shanghai, China
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  • Guoyi Gao,

    Corresponding author
    1. Renji Hospital, Shanghai Jiaotong University School of Medicine, Department of Neurosurgery, Shanghai, China
    • Guoyi Gao, Department of Neurosurgery, Renji Hospital, Shanghai Jiaotong University School of Medicine, 1630 Dongfang Road, Shanghai, 200127, China. guoyigao@gmail.com.

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  • Jiyao Jiang

    1. Renji Hospital, Shanghai Jiaotong University School of Medicine, Department of Neurosurgery, Shanghai, China
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Abstract

This is the protocol for a review and there is no abstract. The objectives are as follows:

This systematic review will try to address the following two goals.

  1. To assess the effectiveness of naloxone on mortality and neurological outcomes in people with acute traumatic brain injury (TBI).

  2. To assess the safety of naloxone in people with acute TBI.