Intervention Review

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Adjuvant chemotherapy for advanced endometrial cancer

  1. Khadra Galaal1,*,
  2. Mansour Al Moundhri2,
  3. Andrew Bryant3,
  4. Alberto D Lopes1,
  5. Theresa A Lawrie4

Editorial Group: Cochrane Gynaecological, Neuro-oncology and Orphan Cancer Group

Published Online: 15 MAY 2014

Assessed as up-to-date: 11 NOV 2013

DOI: 10.1002/14651858.CD010681.pub2


How to Cite

Galaal K, Al Moundhri M, Bryant A, Lopes AD, Lawrie TA. Adjuvant chemotherapy for advanced endometrial cancer. Cochrane Database of Systematic Reviews 2014, Issue 5. Art. No.: CD010681. DOI: 10.1002/14651858.CD010681.pub2.

Author Information

  1. 1

    Princess Alexandra Wing, Royal Cornwall Hospital, Gynaecological Oncology, Truro, UK

  2. 2

    College of Medicine and Health Sciences and Sultan Qaboos University Hospital, Medical Oncology Unit, Department of Medicine, Al-Khod, Oman

  3. 3

    Newcastle University, Institute of Health & Society, Newcastle upon Tyne, UK

  4. 4

    Royal United Hospital, Cochrane Gynaecological, Neuro-oncology and Orphan Cancer Group, Bath, UK

*Khadra Galaal, Gynaecological Oncology, Princess Alexandra Wing, Royal Cornwall Hospital, Truro, TR1 3LJ, UK. k.galaal@nhs.net. khadragalaal@yahoo.co.uk.

Publication History

  1. Publication Status: Edited (no change to conclusions)
  2. Published Online: 15 MAY 2014

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[Figure 1]
Figure 1. Risk of bias summary: review authors' judgements about each risk of bias item for each included trial.
[Figure 2]
Figure 2. Study flow diagram.
[Figure 3]
Figure 3. Forest plot of comparison: 1 Chemotherapy vs radiotherapy, outcome: 1.1 OS (Stage III/IV).
[Figure 4]
Figure 4. Forest plot of comparison: 1 Chemotherapy versus radiotherapy, outcome: 1.6 PFS (Stage III/IV).
[Analysis 1.1]
Analysis 1.1. Comparison 1 Chemotherapy vs radiotherapy, Outcome 1 OS (Stage III/IV).
[Analysis 1.2]
Analysis 1.2. Comparison 1 Chemotherapy vs radiotherapy, Outcome 2 OS (stage III/IV) (unadjusted data).
[Analysis 1.3]
Analysis 1.3. Comparison 1 Chemotherapy vs radiotherapy, Outcome 3 OS (stage III/IV dichotomous).
[Analysis 1.4]
Analysis 1.4. Comparison 1 Chemotherapy vs radiotherapy, Outcome 4 OS (Stage III only).
[Analysis 1.5]
Analysis 1.5. Comparison 1 Chemotherapy vs radiotherapy, Outcome 5 OS (Stage III dichotomous).
[Analysis 1.6]
Analysis 1.6. Comparison 1 Chemotherapy vs radiotherapy, Outcome 6 PFS (Stage III/IV).
[Analysis 1.7]
Analysis 1.7. Comparison 1 Chemotherapy vs radiotherapy, Outcome 7 PFS (stage III/IV dichotomous).
[Analysis 1.8]
Analysis 1.8. Comparison 1 Chemotherapy vs radiotherapy, Outcome 8 PFS (Stage III only).
[Analysis 1.9]
Analysis 1.9. Comparison 1 Chemotherapy vs radiotherapy, Outcome 9 PFS (Stage III dichotomous).
[Analysis 1.10]
Analysis 1.10. Comparison 1 Chemotherapy vs radiotherapy, Outcome 10 Severe adverse events (G3/4).
[Analysis 1.11]
Analysis 1.11. Comparison 1 Chemotherapy vs radiotherapy, Outcome 11 Treatment discontinuation due to toxicity.
[Analysis 1.12]
Analysis 1.12. Comparison 1 Chemotherapy vs radiotherapy, Outcome 12 Treatment-related deaths.
[Analysis 2.1]
Analysis 2.1. Comparison 2 CDP vs CD, Outcome 1 OS (stage III/IV).
[Analysis 2.2]
Analysis 2.2. Comparison 2 CDP vs CD, Outcome 2 PFS (stage III/IV).
[Analysis 2.3]
Analysis 2.3. Comparison 2 CDP vs CD, Outcome 3 Severe adverse events (G3/4).
[Analysis 2.4]
Analysis 2.4. Comparison 2 CDP vs CD, Outcome 4 Treatment discontinuation.