Diagnostic Test Accuracy Protocol
IQCODE for the diagnosis of Alzheimer’s disease dementia and other dementias within a secondary care setting
Editorial Group: Cochrane Dementia and Cognitive Improvement Group
Published Online: 11 OCT 2013
Assessed as up-to-date: 16 JAN 2013
Copyright © 2013 The Cochrane Collaboration. Published by John Wiley & Sons, Ltd.
How to Cite
Quinn TJ, Fearon P, Young C, Noel-Storr AH, McShane R, Stott DJ. IQCODE for the diagnosis of Alzheimer’s disease dementia and other dementias within a secondary care setting (Protocol). Cochrane Database of Systematic Reviews 2013, Issue 10. Art. No.: CD010772. DOI: 10.1002/14651858.CD010772.
- Publication Status: New
- Published Online: 11 OCT 2013
This is the protocol for a review and there is no abstract. The objectives are as follows:
To determine the diagnostic accuracy of the informant-based questionnaire IQCODE, in detection of all-cause (undifferentiated) dementia in adults presenting to secondary-care services.
Where data are available we will describe the following:
- The diagnostic accuracy of IQCODE at various prespecified thresholds. We recognise that various thresholds or cut-off scores have been used to define IQCODE screen positive states. We will describe the properties of IQCODE for the following cut-off scores (rounded where necessary): 3.6; 3.5; 3.4; 3.3. These thresholds have been chosen to represent the range of cut-offs that are commonly used in practice and research; we have been inclusive in our choice of cut-off to maximise available data for review.
- Accuracy of IQCODE for diagnosis of the commonest specific dementia subtype - Alzheimer’s dementia.
- Effects of heterogeneity (see below) on the reported diagnostic accuracy of IQCODE. Potential sources of heterogeneity that we will explore include: age of cohort; case mix of cohort; reason for hospital consultation (dichotomised as 'memory' or 'non-memory' services); technical features of IQCODE; method of dementia diagnosis.