Intervention Protocol

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Glycaemic control for patients with acute coronary syndrome

  1. Régis B Andriolo1,*,
  2. Jose Roberto Ponte Jr2,
  3. Erickson Gomes Gutierrez3,
  4. Brenda NG Silva4,
  5. Luiz Roberto Ramos5

Editorial Group: Cochrane Heart Group

Published Online: 31 OCT 2013

DOI: 10.1002/14651858.CD010811


How to Cite

Andriolo RB, Ponte Jr JR, Gomes Gutierrez E, Silva BNG, Ramos LR. Glycaemic control for patients with acute coronary syndrome (Protocol). Cochrane Database of Systematic Reviews 2013, Issue 10. Art. No.: CD010811. DOI: 10.1002/14651858.CD010811.

Author Information

  1. 1

    Universidade do Estado do Pará, Department of Public Health, Belém, Pará, Brazil

  2. 2

    Universidade do Estado do Pará, Department of Medicine, Belem, Para, Brazil

  3. 3

    Universidade Federal do Para, Department of Medicine, Belem, Para, Brazil

  4. 4

    Centro de Estudos de Medicina Baseada em Evidências e Avaliação Tecnológica em Saúde, Brazilian Cochrane Centre, São Paulo, São Paulo, Brazil

  5. 5

    Escola Paulista de Medicina, Universidade Federal de São Paulo, Department of Preventive Medicine, São Paulo, São Paulo, Brazil

*Régis B Andriolo, Department of Public Health, Universidade do Estado do Pará, Travessa Perebebuí, 2623, Belém, Pará, 66087-670, Brazil. regis.andriolo@gmail.com.

Publication History

  1. Publication Status: Edited (no change to conclusions)
  2. Published Online: 31 OCT 2013

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References

Additional references

Altabas 2012
  • Altabas V, Altabas K, Berković-Cigrovski M, Malosevac S, Vrkljan M, Nikolić Heitzler V. Glucose metabolism disorders in patients with acute coronary syndromes. Acta Clinica Croatica 2012;51(1):71-7. [PUBMED: 22920005]
Angeli 2010
  • Angeli F, Verdecchia P, Karthikeyan G, Mazzotta G, Del Pinto M, Repaci S, et al. New-onset hyperglycemia and acute coronary syndrome: a systematic overview and meta-analysis. Current Diabetes Reviews 2010;6(2):102-10. [PUBMED: 20034367]
Aradi 2013
  • Aradi D, Komócsi A, Vorobcsuk A, Serebruany VL. Impact of clopidogrel and potent P2Y 12 -inhibitors on mortality and stroke in patients with acute coronary syndrome or undergoing percutaneous coronary intervention: a systematic review and meta-analysis. Thrombosis and Haemostasis 2013;109(1):93-101. [PUBMED: 23197191]
Azevedo 2012
  • Azevedo PS, Minicucci MF, Santos PP, Paiva SA, Zornoff LA. Energy metabolism in cardiac remodeling and heart failure. Cardiology in Review 2012;Sep 17:Epub ahead of print. [PUBMED: 22990373]
Bennaghmouch 2013
  • Bennaghmouch N, Ten Berg JM. New oral anticoagulants after acute coronary syndrome. Best Practice & Research. Clinical Haematology 2013;26(2):141-50. [PUBMED: 23953902]
Bennett 2011
  • Bennett MH, Lehm JP, Jepson N. Hyperbaric oxygen therapy for acute coronary syndrome. Cochrane Database of Systematic Reviews 2011, Issue 8. [DOI: 10.1002/14651858.CD004818]
Berndtson 2008
Bernink 2012
  • Bernink FJ, Timmers L, Diamant M, Scholte M, Beek AM, Kamp O, et al. Effect of additional treatment with EXenatide in patients with an Acute Myocardial Infarction: The EXAMI study. International Journal of Cardiology 2012;5273(12):1-2. [PUBMED: 23084550]
Blanco 2012
  • Blanco P, Benzadón M, Cohen Arazi H, Duronto E, Higa C, González MA, et al. Hyperglycemia in acute coronary syndrome: multidisciplinary scientific report [Hiperglucemia en el síndrome coronario agudo: informe científico multidisciplinario]. Medicina 2012;72(2):135-42. [PUBMED: 22522857]
Bronisz 2012
Brownlee 2001
Brunetti 2012
  • Brunetti ND, Sai R, Correale M, De Gennaro L, Di Biase M. Inflammatory activation is related to glucose impairment in diabetics with acute myocardial infarction. International Journal of Cardiology 2013;166(2):533-6. [PUBMED: 23102602]
Bryniarski 2011
  • Bryniarski L, Terlecki M, Bednarek A, Kocowska M, Szynal S, Kawecka-Jaszcz K. The effects of acute hyperglycaemia on the in-hospital and long-term prognosis in patients with an acute coronary syndrome: a pilot study. Kardiologia Polska 2011;69(8):774-81. [PUBMED: 21850617]
Centre for Clinical Practice at NICE (UK) 2011
  • Centre for Clinical Practice at NICE (UK). Hyperglycaemia in Acute Coronary Syndromes: Management of Hyperglycaemia in People with Acute Coronary Syndromes. National Institute for Health and Clinical Excellence: Guidance. London: National Institute for Health and Clinical Excellence (UK), 2011. [PUBMED: 23346606]
Chen 2013
  • Chen YY, Chen J, Hu JW, Yang ZL, Shen YL. Enhancement of lipopolysaccharide-induced toll-like receptor 2 expression and inflammatory cytokine secretion in HUVECs under high glucose conditions. Life Sciences 2013;92(10):582-8. [PUBMED: 23369747]
Cheraghi 2012
  • Cheraghi N, Dai H, Raghuveer G. Vitamin D deficiency is associated with atherosclerosis-promoting risk factor clustering but not vascular damage in children. Medical Science Monitor 2012;18(12):CR687-92. [PUBMED: 23197228]
Cheung 2006
  • Cheung NW, Wong VW, McLean M. The Hyperglycemia: Intensive Insulin Infusion in Infarction (HI-5) study: a randomized controlled trial of insulin infusion therapy for myocardial infarction. Diabetes Care 2006;29(3):765-70. [PUBMED: 16567812]
Cohen 2012
Dasu 2008
  • Dasu MR, Devaraj S, Zhao L, Hwang DH, Jialal I. High glucose induces toll-like receptor expression in human monocytes: mechanism of activation. Diabetes 2008;57(11):3090-8. [PUBMED: 18650365]
De Caterina 2010
  • De Caterina R, Madonna R, Sourij H, Wascher T. Glycaemic control in acute coronary syndromes:prognostic value and therapeutic options. European Heart Journal 2010;31(13):1557-64. [PUBMED: 20519242]
Demircan 2008
  • Demircan S, Yazici M, Diraman E, Demircan G, Kilicaslan F, Durna K, et al. The effect of glucose-insulin-potassium treatment on myocardial oxidative stress in patients with acute coronary syndromes undergoing percutaneous coronary intervention. Coronary Artery Disease 2008;19(2):99-104. [PUBMED: 18300746]
Diaz 1998
  • Díaz R, Paolasso EA, Piegas LS, Tajer CD, Moreno MG, Corvalán R, et al. Metabolic modulation of acute myocardial infarction. The ECLA (Estudios Cardiológicos Latinoamérica) Collaborative Group. Circulation 1998;98(21):2227-34. [PUBMED: 9867443]
Diaz 2007
  • Díaz R, Goyal A, Mehta SR, Afzal R, Xavier D, Pais P, et al. Glucose-insulin-potassium therapy in patients with ST-segment elevation myocardial infarction. Journal of the American Medical Association 2007;298(20):2399-405. [PUBMED: 18042917]
Dragano 2007
  • Dragano N, Verde PE, Moebus S, Stang A, Schmermund A, Roggenbuck U, et al. Subclinical coronary atherosclerosis is more pronounced in men and women with lower socio-economic status: associations in a population-based study Coronary atherosclerosis and social status. European Journal of Cardiovascular Prevention and Rehabilitation 2007;14(4):568-74. [PUBMED: 17667649]
Fang 2012
  • Fang YH, Piao L, Hong Z, Toth PT, Marsboom G, Bache-Wiig P, et al. Therapeutic inhibition of fatty acid oxidation in right ventricular hypertrophy: exploiting Randle's cycle. Journal of Molecular Medicine 2012;90(1):31-43. [PUBMED: 21874543]
Fields 2009
FTT Collaborative Group 1994
  • Fibrinolytic Therapy Trialists' (FTT) Collaborative Group. Indications for fibrinolytic therapy in suspected acute myocardial infarction: collaborative overview of early mortality and major morbidity results from all randomised trials of more than 1000 patients. Lancet 1994;343(8893):311-22. [PUBMED: 7905143]
Fujishiro 2012
  • Fujishiro K, Stukovsky KD, Roux AD, Landsbergis P, Burchfiel C. Occupational gradients in smoking behavior and exposure to workplace environmental tobacco smoke: the multi-ethnic study of atherosclerosis. Journal of Occupational and Environmental Medicine 2012;54(2):136-45. [PUBMED: 22261926]
Fuster 1992
  • Fuster V, Badimon L, Badimon JJ, Chesebro JH. The pathogenesis of coronary artery disease and the acute coronary syndromes (1). New England Journal of Medicine 1992;326(4):242-50. [PUBMED: 1727977]
Ghandi 2007
  • Gandhi GY, Nuttall GA, Abel MD, Mullany CJ, Schaff HV, O'Brien PC, et al. Intensive intraoperative insulin therapy versus conventional glucose management during cardiac surgery: a randomized trial. Annals of Internal Medicine 2007;146(4):233-43. [PUBMED: 17310047]
Giugliano 2012
  • Giugliano RP, Braunwald E. The year in non-ST-segment elevation acute coronary syndrome. Journal of the American College of Cardiology 2012;60(21):2127-39. [PUBMED: 23103037]
Gluckman 2005
  • luckman TJ, Sachdev M, Schulman SP, Blumenthal RS. A simplified approach to the management of non-ST-segment elevation acute coronary syndromes. Journal of American Medical Association 2005;293(3):349-57. [PUBMED: 15657328]
Goodacre 2013
  • Goodacre S, Thokala P, Carroll C, Stevens JW, Leaviss J, Al Khalaf M, et al. Systematic review, meta-analysis and economic modelling of diagnostic strategies for suspected acute coronary syndrome. Health Technology Assessment 2013;1(v-vi):1-188. [PUBMED: 23331845]
Grossman 2013
  • Grossman AN, Opie LH, Beshansky JR, Ingwall JS, Rackley CE, Selker HP. Glucose-insulin-potassium revived: current status in acute coronary syndromes and the energy-depleted heart. Circulation 2013;127(9):1040-8. [PUBMED: 23459576]
Gupta 2011
  • Gupta R, Luo J, Anderson RH, Ray A. Clean indoor air regulation and incidence of hospital admissions for acute coronary syndrome in Kanawha County, West Virginia. Comparative Biochemistry and Physiology 2011;8(4):A77. [PUBMED: 21672401]
Hamm 2011
  • Hamm CW, Bassand JP, Agewall S, Bax J, Boersma E, Bueno H, et al. ESC Guidelines for the management of acute coronary syndromes in patients presenting without persistent ST-segment elevation: The Task Force for the management of acute coronary syndromes (ACS) in patients presenting without persistent ST-segment elevation of the European Society of Cardiology (ESC). European Heart Journal 2011;32(23):2999-3054. [PUBMED: 21873419]
Hanna 2011
  • Hanna EB, Glancy DL. ST-segment depression and T-wave inversion: classification, differential diagnosis, and caveats. Cleveland Clinic Journal of Medicine 2011;78(6):404-14. [PUBMED: 21632912]
Helgadottir 2012
  • Helgadottir A, Gretarsdottir S, Thorleifsson G, Holm H, Patel RS, Gudnason T, et al. Apolipoprotein(a) genetic sequence variants associated with systemic atherosclerosis and coronary atherosclerotic burden but not with venous thromboembolism. Journal of the American College of Cardiology 2010;60(8):722-9. [PUBMED: 22898070]
Higgins 2011
  • Higgins JPT, Green S, editors. Cochrane Handbook for Systematic Reviews of Interventions Version 5.1.0 [updated March 2011]. The Cochrane Collaboration, 2011. Available from www.cochrane-handbook.org.
Iliadis 2011
  • Iliadis F, Kadoglou N, Didangelos T. Insulin and the heart. Diabetes Research and Clinical Practice 2011;93(Suppl 1):S86-91. [PUBMED: 21864757]
Jørgensen 2010
  • Jørgensen CH, Gislason GH, Andersson C, Ahlehoff O, Charlot M, Schramm TK, et al. Effects of oral glucose-lowering drugs on long term outcomes in patients with diabetes mellitus following myocardial infarction not treated with emergent percutaneous coronary intervention - a retrospective nationwide cohort study. Cardiovascular Diabetology 2010;9(54):1-9. [PUBMED: 20843380]
Kageyama 2011
  • Kageyama S, Yokoo H, Tomita K, Kageyama-Yahara N, Uchimido R, Matsuda N, et al. High glucose-induced apoptosis in human coronary artery endothelial cells involves up-regulation of death receptors. Cardiovascular Diabetology 2011;10:73. [PUBMED: 21816064]
Konstantinou 2010
  • Konstantinou DM, Chatzizisis YS, Louridas GE, Parcharidis GE, Giannoglou GD. Non-diabetic hyperglycaemia correlates with angiographic coronary artery disease prevalence and severity. Diabetes & Metabolism 2010;36(5):402-8. [PUBMED: 20594891]
Lahoud 2012
  • Lahoud R, Howe M, Krishnan SM, Zacharias S, Jackson EA. Effect of use of combination evidence-based medical therapy after acute coronary syndromes on long-term outcomes. The American Journal of Cardiology 2012;109(2):159-64. [PUBMED: 22011560]
Lang 1987
Lansky 2012
  • Lansky AJ, Ng VG, Maehara A, Weisz G, Lerman A, Mintz GS, et al. Gender and the extent of coronary atherosclerosis, plaque composition, and clinical outcomes in acute coronary syndromes. Journal of the American College of Cardiology Cardiovascular Imaging 2012;5(3 Suppl):S62-72. [PUBMED: 22421232]
Latour 1997
  • Latour J, Abraira V, Cabello JB, López Sánchez J. Investigation methods in clinical cardiology. IV. Clinical measurements in cardiology: validity and errors of measurements [Métodos de investigación en cardiología clínica (IV). Las mediciones clínicas en cardiología: validez y errores de medición]. Revista Española de Cardiología 1997;50(2):117-28. [PUBMED: 9091999]
Lawrence 2002
  • Lawrence E. Glossary. In: Alberts B, Johnson A, Lewis J, Raff M, Roberts K, Walter P editor(s). Molecular Biology of The Cell. 4th Edition. New York: Garland Science, 2002:1463.
Le Guyader 2009
  • Le Guyader A, Pacheco G, Seaver N, Davis-Gorman G, Copeland J, McDonagh PF. Inhibition of platelet GPIIb-IIIa and P-selectin expression by aspirin is impaired by stress hyperglycemia. Journal of Diabetes and its Complications 2009;23(1):65-70. [PUBMED: 18413191]
Lønborg 2012
  • Lønborg J, Vejlstrup N, Kelbæk H, Bøtker HE, Kim WY, Mathiasen AB, et al. Exenatide reduces reperfusion injury in patients with ST-segment elevation myocardial infarction. European Heart Journal 33;12:1491-9. [PUBMED: 21920963]
Madonna 2008
  • Madonna R, Colella ME, De Caterina R. Glycemic control in the coronary care unit: prognostic value and new therapeutic strategies [Il controllo glicemico in unità coronarica: valore prognostico e nuove strategie terapeutiche]. Giornale Italiano di Cardiologia (Rome) 2008;9(9):603-14. [PUBMED: 18783081]
Maldonado-Rodríguez 2012
  • Maldonado-Rodríguez M, Pérez-López S, Torres-Torres N, Torres-Semprit E, Millán-Aponte I. Outcomes of glycemic control in Hispanic geriatric diabetic patients admitted to a general ward community hospital in Puerto Rico. Boletín de la Asociación Médica de Puerto Rico 2012;104(3):19-23. [PUBMED: 23156888]
Malmberg 1995
  • Malmberg K, Rydén L, Efendic S, Herlitz J, Nicol P, Waldenström A, et al. Randomized trial of insulin-glucose infusion followed by subcutaneous insulin treatment in diabetic patients with acute myocardial infarction (DIGAMI study): effects on mortality at 1 year. Journal of the American College of Cardiology 1995;26(1):57-65. [PUBMED: 7797776]
Malmberg 1996
  • Malmberg K, Rydén L, Hamsten A, Herlitz J, Waldenström A, Wedel H. Effects of insulin treatment on cause-specific one-year mortality and morbidity in diabetic patients with acute myocardial infarction. DIGAMI Study Group. Diabetes Insulin-Glucose in Acute Myocardial Infarction. European Heart Journal 1996;17(9):1337-44. [PUBMED: 8880018]
Malmberg 1997
  • Malmberg K. Prospective randomised study of intensive insulin treatment on long term survival after acute myocardial infarction in patients with diabetes mellitus. DIGAMI (Diabetes Mellitus, Insulin Glucose Infusion in Acute Myocardial Infarction) Study Group. BMJ 1997;314(7093):1512-5. [PUBMED: 9169397]
Malmberg 2005
  • Malmberg K, Ryden L, Wedel H, Birkeland K, Bootsma A, Dickstein K, et al. DIGAMI 2 Investigators. Intense metabolic control by means of insulin in patients with diabetes mellitus and acute myocardial infarction (DIGAMI 2): effects on mortality and morbidity. European Heart Journal 2005;26(7):650-61.
Marzocchi 2012
  • Marzocchi A, Taglieri N, Saia F, Marrozzini C, Rapezzi C, Gallo P, et al. Incidence, treatment and outcome of acute coronary syndromes: a community-based study in the era of myocardial infarction networks. International Journal of Cardiology 2012;157(3):419-22. [PUBMED: 22498420]
McGavigan 2011
  • McGavigan AD, Maxwell PR, Dunn FG. Serological evidence of early remodeling in high-risk non-ST elevation acute coronary syndromes. International Journal of Cardiology 2008;125(1):22-7. [PUBMED: 17433479]
Mehta 2005
  • Mehta SR, Yusuf S, Diaz R, Zhu J, Pais P, Xavier D, et al. Effect of glucose-insulin-potassium infusion on mortality in patients with acute ST-segment elevation myocardial infarction: the CREATE-ECLA randomized controlled trial. Journal of the American Medical Association 2005;293(4):437-46. [PUBMED: 15671428]
Nedkoff 2011
  • Nedkoff LJ, Briffa TG, Preen DB, Sanfilippo FM, Hung J, Ridout SC, et al. Age- and sex-specific trends in the incidence of hospitalized acute coronary syndromes in Western Australia. Circulation. Cardiovascular Quality and Outcomes 2011;4(5):557-64. [PUBMED: 21862718]
Nielsen 2007
  • Nielsen KM, Foldspang A, Larsen ML, Gerdes LU, Rasmussen S, Faergeman O. Estimating the incidence of the acute coronary syndrome: data from a Danish cohort of 138 290 persons. European Journal of Cardiovascular Prevention and Rehabilitation  2007;14(5):608-14. [PUBMED: 17925618]
Nikus 2010
  • Nikus K, Pahlm O, Wagner G, Birnbaum Y, Cinca J, Clemmensen P, et al. Electrocardiographic classification of acute coronary syndromes: a review by a committee of the International Society for Holter and Non-Invasive Electrocardiology. Journal of Electrocardiology 2010;43(2):91-103. [PUBMED: 19913800]
Oldgren 2013
  • Oldgren J, Wallentin L, Alexander JH, James S, Jönelid B, Steg G, et al. New oral anticoagulants in addition to single or dual antiplatelet therapy after an acute coronary syndrome: a systematic review and meta-analysis. European Heart Journal 2013;34(22):1670-80. [PUBMED: 23470494]
Ostrowski 2013
  • Ostrowski SR, Pedersen SH, Jensen JS, Mogelvang R, Johansson PI. Acute myocardial infarction is associated with endothelial glycocalyx and cell damage and a parallel increase in circulating catecholamines. Critical Care 2013;17(1):R32. [PUBMED: 23433357]
Panduranga 2011
  • Panduranga P, Sulaiman K, Al-Lawati J, Al-Zakwani I. Relationship between admitting non-fasting blood glucose and in-hospital mortality stratified by diabetes mellitus among acute coronary syndrome patients in Oman. Heart Views 2011;12(1):12-7. [PUBMED: 21731803]
Petursson 2007
  • Petursson P, Herlitz J, Caidahl K, Gudbjörnsdottir S, Karlsson T, Perers E, et al. Admission glycaemia and outcome after acute coronary syndrome. International Journal of Cardiology 2007;116(3):315-20. [PUBMED: 16854479]
Rajpurohit 2013
  • Rajpurohit N, Garg N, Garg R, Choudhary A, Fresen J, Boren S, et al. Early versus delayed percutaneous coronary intervention for patients with non-ST segment elevation acute coronary syndrome: a meta-analysis of randomized controlled clinical trials. Catheterization and Cardiovascular Interventions 2013;81(7):1255. [PUBMED: 22488783]
Rosenström 2012
  • Rosenström T, Jokela M, Cloninger CR, Hintsanen M, Juonala M, Raitakari O, et al. Associations between dimensional personality measures and preclinical atherosclerosis: the cardiovascular risk in Young Finns study. Journal of Psychosomatic Research 2012;72(5):336-43. [PUBMED: 22469275]
Shuvy 2013
  • Shuvy M, Atar D, Gabriel Steg P, Halvorsen S, Jolly S, Yusuf S, et al. Oxygen therapy in acute coronary syndrome: are the benefits worth the risk?. European Heart Journal 2013;34(22):1630-5. [PUBMED: 23554440]
Srikanth 2012
  • Srikanth S, Ambrose JA. Pathophysiology of coronary thrombus formation and adverse consequences of thrombus during PCI. Current Cardiology Reviews 2012;8(3):168-76. [PUBMED: 22920487]
St Laurent 2011
  • St Laurent P. Acute coronary syndrome: new and evolving therapies. Critical Care Nursing Clinics of North America 2011;23(4):559-71. [PUBMED: 22118114]
Tahir 2013
  • Tahir F, Riaz H, Riaz T, Badshah MB, Riaz IB, Hamza A, et al. The new oral anti-coagulants and the phase 3 clinical trials - a systematic review of the literature. Thrombosis Journal 2013;11(1):18. [PUBMED: 24007323]
Thrall 2007
  • Thrall G, Lane D, Carroll D, Lip GY. A systematic review of the effects of acute psychological stress and physical activity on haemorheology, coagulation, fibrinolysis and platelet reactivity: implications for the pathogenesis of acute coronary syndromes. Thrombosis Research 2007;120(6):819-47. [PUBMED: 17321571]
Trinidad 2011
  • Trinidad R, Gómez J, García Mateo J, Magraner M, Bredy R. Independent association of LDL-C and non HDL-C with acute coronary syndrome in a Hispanic population. Boletín de la Asociación Médica de Puerto Rico 201;103(2):31-4. [PUBMED: 22111468]
Trost 2011
  • Trost JC, Lange RA. Treatment of acute coronary syndrome: Part 1: Non-ST-segment acute coronary syndrome. Critical Care Medicine 2011;39(10):2346-53. [PUBMED: 21602671]
Trost 2012
  • Trost JC, Lange RA. Treatment of acute coronary syndrome: part 2: ST-segment elevation myocardial infarction. Critical Care Medicine 2012;40(6):1939-45. [PUBMED: 22610195]
Undas 2008
  • Undas A, Wiek I, Stêpien E, Zmudka K, Tracz W. Hyperglycemia is associated with enhanced thrombin formation, platelet activation, and fibrin clot resistance to lysis in patients with acute coronary syndrome. Diabetes Care 2008;31(8):1590-5. [PUBMED: 18487475]
van der Vusse 1992
  • van der Vusse GJ, Glatz JF, Stam HC, Reneman RS. Fatty acid homeostasis in the normoxic and ischemic heart. Physiological Reviews 1992;72(4):881-940. [PUBMED: 1438581]
Vivas 2011
  • Vivas D, García-Rubira JC, Bernardo E, Angiolillo DJ, Martín P, Calle-Pascual A, et al. Effects of intensive glucose control on platelet reactivity in patients with acute coronary syndromes. Results of the CHIPS Study [Control de Hiperglucemia y Actividad Plaquetaria en Pacientes con Sindrome Coronario Agudo]. Heart 2011;97(10):803-9. [PUBMED: 21378389]
Vivas 2013
  • Vivas D, Bernardo E, Palacios-Rubio J, Fernández-Ortiz A. How to manage hyperglycemia in an acute coronary syndrome patient. Current Treatment Options in Cardiovascular Medicine 2013;15(1):93-103. [PUBMED: 23096485]
Yang 2010
  • Yang ZH, Peng XD. Insulin resistance and heart injury in rats with insulin resistance or type 2 diabetes mellitus. Acta Cardiologica 2010;65(3):329-35. [PUBMED: 20666272]
Yang 2013
  • Yang DJ, Lee MS, Kim WH, Park HW, Kim KH, Kwon TG, et al. The impact of glucose control on coronary plaque composition in patients with diabetes mellitus. The Journal of Invasive Cardiology 2013;25(3):137-41. [PUBMED: 23468443]
Yatsuya 2010
  • Yatsuya H, Folsom AR, ARIC Investigators. Risk of incident cardiovascular disease among users of smokeless tobacco in the Atherosclerosis Risk in Communities (ARIC) study. American Journal of Epidemiology 2010;172(5):600-5. [PUBMED: 20688904]
Zhao 2010
  • Zhao YT, Weng CL, Chen ML, Li KB, Ge YG, Lin XM, et al. Comparison of glucose-insulin-potassium and insulin-glucose as adjunctive therapy in acute myocardial infarction: a contemporary meta-analysis of randomised controlled trials. Heart 2010;96(20):1622-6. [PUBMED: 20937749]
Zheng 2011
  • Zheng M, Choi SY, Tahk SJ, Lim HS, Yang HM, Choi BJ, et al. The relationship between volumetric plaque components and classical cardiovascular risk factors and the metabolic syndrome a 3-vessel coronary artery virtual histology-intravascular ultrasound analysis. Journal of the American College of Cardiology Cardiovascular Interventions 2011;4(5):503-10. [PUBMED: 21596322]