Add-back therapy with GnRH analogues for uterine fibroids

  • Protocol
  • Intervention

Authors

  • Rafael M Moroni,

    1. University of Sao Paulo, Department of Obstetrics and Gynecology, Medical School of Ribeirao Preto, Ribeirao Preto, Brazil
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  • Wellington P Martins,

    1. University of Sao Paulo, Department of Obstetrics and Gynecology, Medical School of Ribeirao Preto, Ribeirao Preto, Brazil
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  • Rui A Ferriani,

    1. University of Sao Paulo, Department of Obstetrics and Gynecology, Medical School of Ribeirao Preto, Ribeirao Preto, Brazil
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  • Carolina S Vieira,

    1. University of Sao Paulo, Department of Obstetrics and Gynecology, Medical School of Ribeirao Preto, Ribeirao Preto, Brazil
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  • Carolina O Nastri,

    1. University of Sao Paulo, Department of Obstetrics and Gynecology, Medical School of Ribeirao Preto, Ribeirao Preto, Brazil
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  • Francisco José Candido Dos Reis,

    1. University of Sao Paulo, Department of Obstetrics and Gynecology, Medical School of Ribeirao Preto, Ribeirao Preto, Brazil
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  • Luiz Gustavo Brito

    Corresponding author
    1. University of Sao Paulo, Department of Obstetrics and Gynecology, Medical School of Ribeirao Preto, Ribeirao Preto, Brazil
    • Luiz Gustavo Brito, Department of Obstetrics and Gynecology, Medical School of Ribeirao Preto, University of Sao Paulo, Avenida Bandeirantes, 3900, 8th floor ? Monte Alegre Ribeirao Preto, Ribeirao Preto, 14049-900, Brazil. lbrito@usp.br. lgobrito@gmail.com.

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Abstract

This is the protocol for a review and there is no abstract. The objectives are as follows:

To compare the short-term (near 6 months and near 12 months) effectiveness and safety of GnRH analogues versus GnRH analogues plus add-back therapy for women with leiomyomas (uterine fibroids) complaining of excessive uterine bleeding, pelvic pain, or urinary symptoms.