Oral polio vaccine plus inactivated polio vaccine versus oral polio vaccine alone for reducing polio in children under two years of age

  • Protocol
  • Intervention



This is the protocol for a review and there is no abstract. The objectives are as follows:

  • To determine the effects of combined immunisation with OPV and IPV on intestinal mucosal immunity

  • To determine any variation in effect with type of vaccine, number of doses, age at first dose, by human immunodeficiency virus (HIV) status or in high and low income countries

  • To determine any serious adverse outcomes