Interventions to prevent steroid-induced osteoporosis and osteoporotic fractures in Duchenne muscular dystrophy

  • Protocol
  • Intervention

Authors

  • Jennifer M Bell,

    Corresponding author
    1. Queen's University Belfast, Centre for Infection and Immunity, School of Medicine, Dentistry and Biomedical Sciences, Belfast, Northern Ireland, UK
    • Jennifer M Bell, Centre for Infection and Immunity, School of Medicine, Dentistry and Biomedical Sciences, Queen's University Belfast, Room 02.041, 2nd Floor, Mulhouse, Grosvenor Road, Belfast, Northern Ireland, BT12 6BJ, UK. j.m.bell@qub.ac.uk.

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  • Bronagh Blackwood,

    1. Queen's University Belfast, Centre for Infection and Immunity, School of Medicine, Dentistry and Biomedical Sciences, Belfast, Northern Ireland, UK
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  • Michael D Shields,

    1. Queen's University Belfast, Centre for Infection and Immunity, School of Medicine, Dentistry and Biomedical Sciences, Belfast, Northern Ireland, UK
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  • Janet Watters,

    1. Belfast Health and Social Care Trust, GP Out of Hours Service, Belfast, Northern Ireland, UK
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  • Alistair Hamilton,

    1. Belfast Health and Social Care Trust, Withers Orthopaedic Centre, Belfast, Northern Ireland, UK
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  • Timothy Beringer,

    1. Belfast Health and Social Care Trust, Department of Care for the Eldery, Belfast, Northern Ireland, UK
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  • Mark Elliott,

    1. Musgrave Park Hospital, Belfast Health and Social Care Trust, Belfast, UK
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  • Rosaline Quinlivan,

    1. UCL Institute of Neurology and National Hospital for Neurology and Neurosurgery and Great Ormond Street, MRC Centre for Neuromuscular Diseases and Dubowitz Neuromuscular Centre, London, UK
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  • Sandya Tirupathi

    1. Royal Belfast Hospital for Sick Children, Paediatric Neurology, Belfast, UK
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Abstract

This is the protocol for a review and there is no abstract. The objectives are as follows:

Primary objective

To assess the effects of interventions to delay or treat osteoporosis in DMD patients treated with glucocorticoid steroids.

Secondary objectives

To assess the effects of interventions to delay or treat osteoporosis in DMD on the frequency of vertebral fragility fractures and long bone fractures in DMD patients treated with glucocorticoid steroids.