Interventions for chronic non-hypovolaemic hypotonic hyponatraemia

  • Protocol
  • Intervention

Authors

  • Evi V Nagler,

    Corresponding author
    1. University Hospital Ghent, Renal Division, Department of Internal Medicine, Ghent, Belgium
    2. European Renal Best Practice (ERBP), guidance issuing body of the European Renal Association – European Dialysis and Transplant Association (ERA-EDTA), Ghent, Belgium
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  • Maria C Haller,

    1. European Renal Best Practice (ERBP), guidance issuing body of the European Renal Association – European Dialysis and Transplant Association (ERA-EDTA), Ghent, Belgium
    2. Krankenhaus Elisabethinen Linz, Department for Internal Medicine III, Nephrology & Hypertension Diseases, Transplantation Medicine & Rheumatology, Linz, Austria
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  • Wim Van Biesen,

    1. University Hospital Ghent, Renal Division, Department of Internal Medicine, Ghent, Belgium
    2. guidance issuing body of the European Renal Association – European Dialysis and Transplant Association (ERA-EDTA), European Renal Best Practice (ERBP), Ghent, Belgium
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  • Raymond Vanholder,

    1. University Hospital Ghent, Renal Division, Department of Internal Medicine, Ghent, Belgium
    2. European Renal Best Practice (ERBP), guidance issuing body of the European Renal Association – European Dialysis and Transplant Association (ERA-EDTA), Ghent, Belgium
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  • Jonathan C Craig,

    1. The University of Sydney, Sydney School of Public Health, Sydney, NSW, Australia
    2. The Children's Hospital at Westmead, Cochrane Renal Group, Centre for Kidney Research, Westmead, NSW, Australia
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  • Angela C Webster

    1. The University of Sydney, Sydney School of Public Health, Sydney, NSW, Australia
    2. The Children's Hospital at Westmead, Cochrane Renal Group, Centre for Kidney Research, Westmead, NSW, Australia
    3. The University of Sydney at Westmead, Centre for Transplant and Renal Research, Westmead Millennium Institute, Westmead, NSW, Australia
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Abstract

This is the protocol for a review and there is no abstract. The objectives are as follows:

This review aims to look at the benefits and harms of interventions for chronic non-hypovolaemic hypotonic hyponatraemia when compared with placebo, no treatment or head-to-head.

The review aims to determine if benefits and harms vary in absolute or relative terms dependent on the specific compound within a drug class, on the dosage used, or the underlying disorder causing the hyponatraemia.