Safety of off-label erythropoiesis-stimulating agents for critically ill patients

  • Protocol
  • Intervention



This is a protocol for a Cochrane Review (Intervention). The objectives are as follows:

With a focus on safety, we aim to assess the effects of ESAs (ESAs alone or in combination) compared with placebo, no treatment or a different active treatment regimen when administered off-label to critically ill patients. We will further describe and explore heterogeneity and will assess the influence of bias on the robustness of our effect estimates.