Intervention Protocol

Comparison of different platelet count thresholds to guide administration of prophylactic platelet transfusion for preventing bleeding in patients with haematological disorders after chemotherapy or stem cell transplantation

  1. Lise J Estcourt1,*,
  2. Simon Stanworth1,
  3. Carolyn Doree2,
  4. Marialena Trivella3,
  5. Sally Hopewell3,
  6. Michael F Murphy4,
  7. Alan Tinmouth5

Editorial Group: Cochrane Haematological Malignancies Group

Published Online: 19 MAR 2014

DOI: 10.1002/14651858.CD010983


How to Cite

Estcourt LJ, Stanworth S, Doree C, Trivella M, Hopewell S, Murphy MF, Tinmouth A. Comparison of different platelet count thresholds to guide administration of prophylactic platelet transfusion for preventing bleeding in patients with haematological disorders after chemotherapy or stem cell transplantation (Protocol). Cochrane Database of Systematic Reviews 2014, Issue 3. Art. No.: CD010983. DOI: 10.1002/14651858.CD010983.

Author Information

  1. 1

    NHS Blood and Transplant, Haematology/Transfusion Medicine, Oxford, UK

  2. 2

    NHS Blood and Transplant, Systematic Review Initiative, Oxford, UK

  3. 3

    University of Oxford, Centre for Statistics in Medicine, Oxford, UK

  4. 4

    John Radcliffe Hospital, NHS Blood and Transplant, Oxford, UK

  5. 5

    The Ottawa Health Research Institute and the University of Ottawa, Medicine (hematology) and Pathology Centre for Transfusion Research, Ottawa, Ontario, Canada

*Lise J Estcourt, Haematology/Transfusion Medicine, NHS Blood and Transplant, Level 2, John Radcliffe Hospital, Headington, Oxford, OX3 9BQ, UK. lise.estcourt@nhsbt.nhs.uk. lestcourt@doctors.org.uk.

Publication History

  1. Publication Status: New
  2. Published Online: 19 MAR 2014

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Abstract

  1. Top of page
  2. Abstract

This is the protocol for a review and there is no abstract. The objectives are as follows:

To determine whether different platelet transfusion thresholds for administration of prophylactic platelet transfusions (platelet transfusions given to prevent bleeding) affect the efficacy and safety of prophylactic platelet transfusions in preventing bleeding in patients with haematological disorders after chemotherapy with or without stem cell transplantation.