Intervention Protocol

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Exercise therapy for chronic fatigue syndrome (individual patient data)

  1. Lillebeth Larun1,*,
  2. Jan Odgaard-Jensen2,
  3. Kjetil G. Brurberg1,
  4. Trudie Chalder3,
  5. Marianne Dybwad4,
  6. Rona E Moss-Morris5,
  7. Michael Sharpe6,
  8. Karen Wallman7,
  9. Alison Wearden8,
  10. Peter D White9,
  11. Paul P Glasziou10

Editorial Group: Cochrane Depression, Anxiety and Neurosis Group

Published Online: 1 APR 2014

Assessed as up-to-date: 14 MAR 2014

DOI: 10.1002/14651858.CD011040


How to Cite

Larun L, Odgaard-Jensen J, Brurberg KG, Chalder T, Dybwad M, Moss-Morris RE, Sharpe M, Wallman K, Wearden A, White PD, Glasziou PP. Exercise therapy for chronic fatigue syndrome (individual patient data) (Protocol). Cochrane Database of Systematic Reviews 2014, Issue 4. Art. No.: CD011040. DOI: 10.1002/14651858.CD011040.

Author Information

  1. 1

    Norwegian Knowledge Centre for the Health Services, Primary Health Care Unit, Oslo, Norway

  2. 2

    Norwegian Knowledge Centre for the Health Services, Global Health Unit, Oslo, Norway

  3. 3

    Institute of Psychiatry, King's College London, Chronic Fatigue Service, Department of Psychological Medicine, London, UK

  4. 4

    Sunnaas Rehabilitation Hospital, Nesoddtangen, Norway

  5. 5

    Institute of Psychiatry, King's College London, Section of Health Psychology, London, UK

  6. 6

    University of Oxford, Department of Psychiatry, Oxford, UK

  7. 7

    The University of Western Australia, School of Sport Science, Exercise and Health, Crawley, Australia

  8. 8

    University of Manchester, School of Psychological Sciences, Manchester, UK

  9. 9

    Barts and The London School of Medicine and Dentistry, Queen Mary University of London, Centre for Psychiatry, London, UK

  10. 10

    Bond University, Centre for Research in Evidence-Based Practice (CREBP), Faculty of Health Sciences and Medicine, Gold Coast, Queensland, Australia

*Lillebeth Larun, Primary Health Care Unit, Norwegian Knowledge Centre for the Health Services, PO Box 7004, St Olav's plass, Oslo, N-0130, Norway. Lillebeth.Larun@kunnskapssenteret.no.

Publication History

  1. Publication Status: Edited (no change to conclusions)
  2. Published Online: 1 APR 2014

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References

Additional references

Adams 2009
Bland 1997
  • Bland JM, Kerry SM. Statistics notes. Trials randomised in clusters. BMJ 1997;315:600.
BMJ Best Practice 2013
  • BMJ Best Practice. Chronic fatigue syndrome Step-by step. http://bestpractice.bmj.com/best-practice/monograph/277/treatment/step-by-step.html 2013.
Brozek 2008
  • Brozek J, Oxman A, Schünemann H. GRADEpro. 3.2 for Windows. Brozek J, Oxman A, Schünemann H, 2008.
Brurberg 2014
  • Brurberg KJ, Fonhus MS, Larun L, Flottorp S, Malterud K. Case definitions for chronic fatigue syndrome/myalgic encephalomyelitis (CFS/ME): a systematic review. BMJ Open 2014;4(2):e003973. [DOI: 10.1136/bmjopen-2013-003973]
Buysse 1989
  • Buysse DJ, Reynolds CF, Monk TH, Berman SR, Kupfer DJ. The Pittsburgh Sleep Quality Index: a new instrument for psychiatric practice and research. Psyciatric Research 989;1(28):193-213.
Carruthers 2011
Chalder 1993
Christely 2012
  • Christely Y, Duffy T, Martin CR. A review of the definitional criteria for chronic fatigue syndrome. Clinical Practice 2012;18:25-31. [DOI: 10.1111/j.1365-2753.2010.01512.x]
Deale 1997
  • Deale A, Chalder T, Marks I, Wessely, S. Cognitive behavior therapy for chronic fatigue syndrome: a randomized controlled trial. American Journal of Psychiatry 1997;154(3):408-14.
Divine 1992
Edmonds 2004
  • Edmonds M, McGuire H, Price J. Exercise therapy for chronic fatigue syndrome. Cochrane Database of Systematic Reviews 2004, Issue 3. [DOI: 10.1002/14651858.CD003200.pub2]
Egger 1997
  • Egger M, Smith GD, Schneider M, Minder C. Bias in meta-analysis detected by a simple, graphical test. BMJ 1997;315:629-34.
Elbourne 2002
  • Elbourne DR, Altman DG, Higgins JP, Curtin F, Worthington HV, Vail A. Meta-analyses involving cross-over trials: methodological issues. International Journal of Epidemiology 2002;31:140-9.
European Union Clinical Trials Directive 2001
  • The European Parliament and the Council of the European Union. DIRECTIVE 2001/20/EC European Parliament and the Council of the European Union of 4 April 2001. Official Journal of the European Communities 2001;L 121/34. http://www.eortc.be/services/doc/clinical-eu-directive-04-april-01.pdf.
Finch 2002
  • Finch E, Brooks D, Stratford PW, Mayo N. Physical Rehabilitation Outcome Measures. A Guide to Clinical Decision Making. 2nd Edition. Canadian Physiotherapy Association, Canada: Lippincott, Williams and Wilkins, 2002.
Fukuda 1994
  • Fukuda K, Straus SE, Hickie I, Sharpe MC, Dobbins JG, Komaroff A. The chronic fatigue syndrome; a comprehensive approach to its definition and study. Annals of Internal Medicine 1994;121(12):953-9.
Fulcher 2000
  • Fulcher KY, White PD. Strength and physiological response to exercise in patients with chronic fatigue syndrome. Journal of Neurology, Neurosurgery and Psychiatry 2000;69:302-7.
Gulliford 1999
  • Gulliford MC, Ukoumunne OC, Chinn S. Components of variance and intra class correlations for the design of community-based surveys and intervention studies: data from the Health Survey for England 1994. American Journal of Epidemiology 1999;149:876-83.
Guy 1976
  • Guy WR. ECDEU Assessment Manual for Psychopharmacology. Rockville, MD: National Institute of Mental Health, 1976.
Guyatt 2008
  • Guyatt GH, Oxman AD, Vist GE, Kunz R, Falck-Ytter Y, Alonso-Coello P, et al. GRADE: an emerging consensus on rating quality of evidence and strength of recommendations. BMJ 2008;336(7650):924-6.
Higgins 2003
Higgins 2011a
  • Higgins JPT, Altman DG, Sterne JAC (editors). Chapter 8: Assessing risk of bias in included studies. In: Higgins JPT, Green S editor(s). Cochrane Handbook for Systematic Reviews of Interventions Version 5.1.0 [updated March 2011] Available from www.cochrane-handbook.org. The Cochrane Collaboration, 2011.
Higgins 2011b
  • Higgins JPT, Green S (editors). Cochrane Handbook for Systematic Reviews of Interventions Version 5.1.0 [updated March 2011]. The Cochrane Collaboration. Available from www.cochrane-handbook.org, 2011.
ICMJE 2014
  • International Committee of Medical Journal Editors (ICMJE). Recommendations for the Conduct, Reporting, Editing and Publication of Scholarly Work in Medical Journals (ICMJE Recommendations). http://www.icmje.org/recommendations/ 2011-2013.
Krupp 1989
  • Krupp LB, LaRocca NG, Muir-Nash J, Steinberg AD. The Fatigue Severity Scale. Application to patients with multiple sclerosis and systemic lupus erythematosus. Archives of Neurology 1989;46:1121-3.
Larun 2011
  • Larun L, Malterud K. Finding the right balance of physical activity. A focus group study about experiences among patients with chronic fatigue syndrome. Patient Education and Counseling 2011;83:222-6.
Medical Research Council 2003
Moss-Morris 2005
  • Moss-Morris R, Sharon C, Tobin R, Baldi JC. A randomized controlled graded exercise trial for chronic fatigue syndrome: outcomes and mechanisms of change. Journal of Health Psychology 2005;10(2):245-59.
Moss-Morris 2010
  • Moss-Morris R, Spence MJ, Hou R. The pathway form glandular fever to chronic fatigue syndrome: can the cognitive behavioural model provide the map?. Psychological Medicine 2010;00:1-9.
Moss-Morris 2012
  • Moss-Morris R, Deary V, Castell B. Chronic fatigue syndrome. In: Barnes M, Good D editor(s). Neuro-Rehabilitation in the Handbook of Clinical Neurology 3rd Series. Elsevier, 2012:303-14.
Mother 2009
  • Moher D, Liberati A, Tetzlaff J, Altman DG. Preferred Reporting Items for Systematic Reviews and Meta-Analyses: The PRISMA Statement. PLoS Medicine 2009;6(7):e1000097. [DOI: 10.1371/journal.pmed1000097]
Mundt 2002
NICE 2007
  • National Collaborating Center for Primary Care. NICE clinical guideline 53. Chronic fatigue syndrome/myalgic encephalomyelitis (or encephalopathy): diagnosis and management of CFS/ME in adults and children. National Institute for Health and Clinical Excellence 2007.
Nijs 2011
  • Nijs J, Meeus M, Van Oosterwijck J, Ickmans K, Moorkens G, Hans G, et al. In the mind or the brain? Scientific evidence for central sensitisation in chronic fatigue syndrome. European Journal of Clinical Investigation 2011;42:203-11. [DOI: 10.1111/j.1365-2362.2011.02575.x]]
Nunez 2011
OED 2012
Price 2008
  • Price JR, Mitchell E, Tidy E, Hunot V. Cognitive behaviour therapy for chronic fatigue syndrome in adults. Cochrane Database of Systematic Reviews 2008, Issue 3. [DOI: 10.1002/14651858.CD001027.pub2]
Prins 2006
Ranjith 2005
Rietberg 2004
Riley 2008
Riley 2010
SAS 2009
Sharpe 1991
  • Sharpe M, Archard L, Banatvala J, Borysiewicz LK, Clare AW, David A, et al. Chronic fatigue syndrome: guidelines for research. Journal of the Royal Society of Medicine 1991;84(2):118-21.
Spence 2005
  • Spence M, Moss-Morris R, Chalder T. The Behavioural Responses to Illness Questionnaire (BRIQ): a new predictive measure of medically unexplained symptoms following acute infection. Psychological Medicine 2005;35(4):583-93.
Sterne 2011
  • Sterne JAC, Egger M, Moher D (editors). Chapter 10: addressing reporting biases. In: Higgins JPT, Green S editor(s). Cochrane Handbook for Systematic Reviews of Interventions Version 5.1.0 [updated March 2011] Available from www.cochrane-handbook.org. The Cochrane Collaboration, 2011.
Stewart 2011
  • Stewart LA, Tierney JF, Clarke M. Chapter 18: Reviews of individual patient data. In: Higgins JPT, Green S editor(s). Cochrane Handbook of Systematic Reviews, version 5.1.0. The Cochrane Collaboration, 2011.
Takken 2008
  • Takken T, Van Brussel M, Engelbert RH, van der Net JJ, Kuis W, Helders PPJM. Exercise therapy in juvenile idiopathic arthritis. Cochrane Database of Systematic Reviews 2008, Issue 2. [DOI: 10.1002/14651858.CD005954.pub2]
The London Criteria 1994
  • The London criteria. Report on chronic fatigue syndrome (CFS), post viral fatigue syndrome (PVFS) and myalgic encephalomyelitis (ME). Westcare, Bristol: The National Task Force 1994.
Tierney 2005
  • Tierney JF, Stewart LA. Investigating patient exclusion bias in meta-analysis. International Journal of Epidemiology 2005;34(1):79-87.
Tsang 2003
Twisk 2009
  • Twisk FNM, Maes M. A review on cognitive behavorial therapy (CBT) and graded exercise therapy (GET) in myalgicencephalomyelitis (ME)/chronic fatigue syndrome(CFS). Neuroendocrinology Letters 2009;30(3):284-99.
Ware 1992
Zigmond 1983