This study investigated the utility of the Early Screening Profiles (ESP; Harrison, 1990) to differentiate between preschoolers at risk for cognitive delays (n= 49) and non-risk preschoolers (n= 44). Step-wise discriminant function analysis was performed using the ESP Profiles and Total Screening scores as the predictors of group membership. The Total Screening score, by itself, was found to correctly classify approximately 81% of the preschoolers. In a separate discriminant analysis, the Cognitive/Language and Motor profiles were required to maintain a similar level of correct classifications as the ESP Total Screening score. © 2001 John Wiley & Sons, Inc.