Peptides Bound to Silicone Membranes and 3D Microfabrication for Cardiac Cell Culture (pages 461–463)
S. Boateng, S.S. Lateef, C. Crot, D. Motlagh, T. Desai, A.M. Samarel, B. Russell and L. Hanley
Article first published online: 12 MAR 2002 | DOI: 10.1002/1521-4095(20020318)14:6<461::AID-ADMA461>3.0.CO;2-S
Silicone membranes are frequently used as flexible cell culture substrates in studies of cardiac mechano-biology. Such physiologically relevant models of cells in vitro are required for fundamental studies of the basic mechanisms of mechanical transduction at the cellular level. Microfabrication and peptide binding, as well as other advances in surface modification and microfabrication that promise further development in flexible cell culture systems, are discussed.