Evidence of saxitoxin derivatives as causative agents in the 1997 mass mortality of monk seals in the Cape Blanc Peninsula
Article first published online: 13 DEC 2000
Copyright © 1999 John Wiley & Sons, Ltd.
Volume 7, Issue 6, pages 311–315, November/December 1999
How to Cite
Reyero, M., Cacho, E., Martínez, A., Vázquez, J., Marina, A., Fraga, S. and Franco, J. M. (1999), Evidence of saxitoxin derivatives as causative agents in the 1997 mass mortality of monk seals in the Cape Blanc Peninsula. Nat. Toxins, 7: 311–315. doi: 10.1002/1522-7189(199911/12)7:6<311::AID-NT75>3.0.CO;2-I
- Issue published online: 13 DEC 2000
- Article first published online: 13 DEC 2000
- Manuscript Accepted: 13 JUN 2000
- Manuscript Received: 16 DEC 1999
- Comisión Interministerial de Ciencia y Tecnología. Grant Number: ALI95-1012-C05-01
- monk seals;
- mass mortality;
- PSP toxins;
Monk seals in Cape Blanc (Western Sahara coast) suffered a mass mortality during May–July 1997 which was attributed to a morbillivirus. High performance liquid chromatography (HPLC) analysis on tissues of seals killed during the outbreak and on related fauna showed peaks with retention times coincident with those of some saxitoxin derivatives but their identity was not proved. Here we present results of further HPLC analyses that unambiguously prove the identity of these toxins by mass spectrometry (MS), supporting the hypothesis that this mortality of monk seals was caused by biotoxins rather than by a morbillivirus. Copyright © 1999 John Wiley & Sons, Ltd.