Chapter 15. Apoptosis

  1. Gerhard Krauss

Published Online: 17 DEC 2001

DOI: 10.1002/3527600051.ch15

Biochemistry of Signal Transduction and Regulation, Second Edition

Biochemistry of Signal Transduction and Regulation, Second Edition

How to Cite

Krauss, G. (2001) Apoptosis, in Biochemistry of Signal Transduction and Regulation, Second Edition, Wiley-VCH Verlag GmbH, Weinheim, FRG. doi: 10.1002/3527600051.ch15

Author Information

  1. Laboratorium für Biochemie, Universität Bayreuth, D-95440 Bayreuth, Germany

Publication History

  1. Published Online: 17 DEC 2001
  2. Published Print: 17 JUL 2001

ISBN Information

Print ISBN: 9783527303786

Online ISBN: 9783527600052

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Keywords:

  • apoptosis;
  • caspases;
  • Bcl-2 proteins;
  • cofactors of caspase activation;
  • stress-mediated apoptosis;
  • cytochrome c/Apaf1 pathway

Summary

  • Basic functions of apoptosis

  • Apoptosis in the nematode Caenorhabditis elegans

  • Components of the apoptotic program in mammals

    • Caspases: death by proteolysis

    • The family of Bcl-2 proteins

    • Cofactors of caspase activation

    • Intracellular regulation

  • Stress-mediated apoptosis: the cytochrome c/Apaf1 pathway

  • Death-receptor-triggered apoptosis

  • Apoptosis and cellular signaling pathways