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Protein Dynamics — Concepts and Experimental Tools

  1. Hans Frauenfelder

Published Online: 15 AUG 2009

DOI: 10.1002/3527600434.eap664

Encyclopedia of Applied Physics

Encyclopedia of Applied Physics

How to Cite

Frauenfelder, H. 2009. Protein Dynamics — Concepts and Experimental Tools. Encyclopedia of Applied Physics. .

Author Information

  1. Los Alamos National Laboratory

Publication History

  1. Published Online: 15 AUG 2009


Most textbooks and publications show proteins in a unique structure and naked, without hydration shell and bulk environment. In reality, proteins can assume a very large number of different conformations. They fluctuate continuously and are controlled by the hydration shell and the solvent. Without these fluctuations, proteins could not work. This chapter gives a brief overview of protein dynamics and cites references where more information can be found.


  • conformational substates;
  • energy landscape;
  • α and β fluctuations;
  • proteinquakes;
  • slaving