Raman Spectroscopy in Medicine
Published Online: 15 AUG 2009
Copyright © 2003 by Wiley-VCH Verlag GmbH & Co. KGaA. All rights reserved.
Encyclopedia of Applied Physics
How to Cite
Krafft, C., Rösch, P. and Popp, J. 2009. Raman Spectroscopy in Medicine. Encyclopedia of Applied Physics.
- Published Online: 15 AUG 2009
Raman spectroscopy is an emerging tool in medicine to study tissues and body fluids. This contribution gives an overview of experimental techniques and selected applications. The methodological section presents Raman spectra of biomolecules, the near-infrared advantage, combination with microscopy, Raman imaging, fiber-optic probes, and signal enhancement principles. Pathological applications of Raman spectroscopy were reported in the context of oncology, for mineralized tissue such as bone, teeth, and calculi in organs, for blood vessels, for skin, and for the visual system. Raman spectroscopy in clinical chemistry was applied to determine glucose in diabetic patients; to analyze serum, hair and nails; and to investigate malaria.
- Raman imaging;
- fiber-optic probe;
- Raman spectroscopy;
- Raman spectra;
- Raman microscopy