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Biomolecular Structures by Solution Nuclear Magnetic Resonance

  1. Tharin M. A. Blumenschein

Published Online: 15 DEC 2009

DOI: 10.1002/3527600434.eap691

Encyclopedia of Applied Physics

Encyclopedia of Applied Physics

How to Cite

Blumenschein, T. M. A. 2009. Biomolecular Structures by Solution Nuclear Magnetic Resonance. Encyclopedia of Applied Physics. 963–987.

Author Information

  1. University of East Anglia, School of Chemistry, Norwich, UK

Publication History

  1. Published Online: 15 DEC 2009

Abstract

The article contains sections titled:

  • 1
    Introduction
  • 2
    Spectra Acquisition
    • 2.1
      Nuclei
    • 2.2
      Sample Preparation
    • 2.3
      Pulse Sequences and Processing Strategies
  • 3
    Chemical Shift Assignment
    • 3.1
      Chemical Shift Assignment in Proteins
    • 3.2
      Chemical Shift Assignment in Nucleic Acids
    • 3.3
      Chemical Shift Assignment in Carbohydrates
  • 4
    Structural Restraints
    • 4.1
      Nuclear Overhauser Effect
    • 4.2
      Torsion Angles
    • 4.3
      Residual Dipolar Couplings (RDCs)
    • 4.4
      Hydrogen Bonds
    • 4.5
      Paramagnetic Centers
    • 4.6
      Structural Information from Chemical Shifts
  • 5
    Molecular Modeling and Structure Calculation

Keywords:

  • biological macromolecules;
  • NMR spectroscopy;
  • isotopic labelling;
  • protein structure;
  • nucleic acids