Standard Article

Mass Spectrometry

  1. Jürgen H. Gross

Published Online: 15 DEC 2009

DOI: 10.1002/3527600434.eap692

Encyclopedia of Applied Physics

Encyclopedia of Applied Physics

How to Cite

Gross, J. H. 2009. Mass Spectrometry. Encyclopedia of Applied Physics. 989–1053.

Author Information

  1. University of Heidelberg, Institute of Organic Chemistry, Heidelberg, 69120, Germany

Publication History

  1. Published Online: 15 DEC 2009

Abstract

The article contains sections titled:

  • 1
    Introduction
    • 1.1
      Concept of Mass Spectrometry
    • 1.2
      Goal of Mass Spectrometry
    • 1.3
      Mass Spectrometry at a Glance
    • 1.4
      Aims and Scope
  • 2
    The Role of Isotopes in Mass Spectrometry
    • 2.1
      Isotopes
    • 2.2
      Atomic Mass Scale
    • 2.3
      Isotopic Patterns
    • 2.4
      Accurate Mass
    • 2.5
      Calculation of Atomic Weights and Molecular Weights
  • 3
    Mass Spectrometric Methods
  • 4
    Ionization Processes
    • 4.1
      Formation of Positive Radical Ions
      • 4.1.1
        Electron Ionization
      • 4.1.2
        Photoionization
      • 4.1.3
        Penning Ionization
      • 4.1.4
        Charge Transfer
      • 4.1.5
        Field Ionization
    • 4.2
      Formation of Positive Ions
      • 4.2.1
        Proton Transfer
      • 4.2.2
        Electrophilic Addition
      • 4.2.3
        Anion Abstraction
    • 4.3
      Formation of Negative Radical Ions
      • 4.3.1
        Electron Capture
    • 4.4
      Formation of Negative Ions
      • 4.4.1
        Nucleophilic Addition
      • 4.4.2
        Cation Abstraction
  • 5
    Isotopic and Elemental Analysis
    • 5.1
      Thermal Ionization
    • 5.2
      Spark Source
    • 5.3
      Glow Discharge
    • 5.4
      Inductively Coupled Plasma
    • 5.5
      Accelerator Mass Spectrometry
  • 6
    Ionization of Gaseous Molecules in Vacuum
    • 6.1
      Electron Ionization
    • 6.2
      Chemical Ionization
    • 6.3
      Field Ionization
  • 7
    Desorption/Ionization
    • 7.1
      Field Desorption
    • 7.2
      Fast Atom Bombardment and Liquid Secondary Ion Mass Spectrometry
    • 7.3
      Laser Desorption/Ionization
    • 7.4
      Matrix-Assisted Laser Desorption/Ionization
  • 8
    Ion Formation at Atmospheric Pressure
    • 8.1
      Atmospheric Pressure Ionization
    • 8.2
      Electrospray Ionization
    • 8.3
      Atmospheric Pressure Chemical Ionization and Atmospheric Pressure Photoionization
    • 8.4
      Atmospheric Pressure MALDI
    • 8.5
      Desorption Electrospray
    • 8.6
      Direct Analysis in Real Time
  • 9
    Activation Methods for Tandem Mass Spectrometry
  • 10
    Acronyms

Keywords:

  • mass spectrometry;
  • gas chromatography;
  • Penning ionization;
  • soft ionization method;
  • chemical ionization;
  • ionization efficiency