Chapter 14. Evolutionary Generation of Enzymes with Novel Substrate Specificities

  1. Dr. Susanne Brakmann2,
  2. Prof. Dr. Kai Johnsson3
  1. Prof. Dr. Uwe T. Bornscheuer

Published Online: 28 MAR 2003

DOI: 10.1002/3527600647.ch14

Book Title

Directed Molecular Evolution of Proteins: or How to Improve Enzymes for Biocatalysis

Directed Molecular Evolution of Proteins: or How to Improve Enzymes for Biocatalysis

Additional Information

How to Cite

Bornscheuer, U. T. (2003) Evolutionary Generation of Enzymes with Novel Substrate Specificities, in Directed Molecular Evolution of Proteins: or How to Improve Enzymes for Biocatalysis (eds S. Brakmann and K. Johnsson), Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim, FRG. doi: 10.1002/3527600647.ch14

Editor Information

  1. 2

    AG “Angewandte Molekulare Evolution”, Institut für Spezielle Zoologie, Universität Leipzig, Talstraße 33, D-04103 Leipzig, Germany

  2. 3

    Insitute of Molecular and Biological Chemistry, Swiss Federal Institute of Technology Lausanne, CH-1015 Lausanne, Switzerland

Author Information

  1. Institut für Chemie und Biochemie, Ernst-Moritz-Arndt-Universität, Soldmannstraße 16, 17487 Greifswald, Germany

Publication History

  1. Published Online: 28 MAR 2003
  2. Published Print: 22 APR 2002

ISBN Information

Print ISBN: 9783527304233

Online ISBN: 9783527600649

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CHAPTER TOOLS

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Keywords:

  • evolutionary enzyme generation;
  • substrate specificities

Summary

This chapter contains sections titled:

  • Introduction

  • General Considerations

  • Examples

    • Group 1

    • Group 2

    • Group 3

  • Conclusions

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