Chapter 2. Evolutionary Biotechnology – From Ideas and Concepts to Experiments and Computer Simulations

  1. Dr. Susanne Brakmann2,
  2. Prof. Dr. Kai Johnsson3
  1. Prof. Dr. Peter Schuster

Published Online: 28 MAR 2003

DOI: 10.1002/3527600647.ch2

Book Title

Directed Molecular Evolution of Proteins: or How to Improve Enzymes for Biocatalysis

Directed Molecular Evolution of Proteins: or How to Improve Enzymes for Biocatalysis

Additional Information

How to Cite

Schuster, P. (2003) Evolutionary Biotechnology – From Ideas and Concepts to Experiments and Computer Simulations, in Directed Molecular Evolution of Proteins: or How to Improve Enzymes for Biocatalysis (eds S. Brakmann and K. Johnsson), Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim, FRG. doi: 10.1002/3527600647.ch2

Editor Information

  1. 2

    AG “Angewandte Molekulare Evolution”, Institut für Spezielle Zoologie, Universität Leipzig, Talstraße 33, D-04103 Leipzig, Germany

  2. 3

    Insitute of Molecular and Biological Chemistry, Swiss Federal Institute of Technology Lausanne, CH-1015 Lausanne, Switzerland

Author Information

  1. Institut für Theoretische Chemie und Strahlenchemie, Universität Wien, Währingerstraße 17, A-1090 Wien, Österreich

Publication History

  1. Published Online: 28 MAR 2003
  2. Published Print: 22 APR 2002

ISBN Information

Print ISBN: 9783527304233

Online ISBN: 9783527600649

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CHAPTER TOOLS

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Keywords:

  • evolutionary biotechnology;
  • computer simulations;
  • evolution;
  • natural selection;
  • population genetics;
  • magic molecules;
  • neutral networks;
  • multi-stable molecules;
  • structure mapping

Summary

This chapter contains sections titled:

  • Evolution in vivo From Natural Selection to Population Genetics

  • Evolution in vitro From Kinetic Equations to Magic Molecules

  • Evolution in silico From Neutral Networks to Multi-stable Molecules

  • Sequence Structure Mappings of Proteins

  • Concluding Remarks

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