Chapter 6. The Modification of Ligand Reactivity by Complex Formation

  1. Prof. Ralph G. Wilkins

Published Online: 2 JUN 2003

DOI: 10.1002/3527600825.ch6

Kinetics and Mechanism of Reactions of Transition Metal Complexes, 2nd Edition

Kinetics and Mechanism of Reactions of Transition Metal Complexes, 2nd Edition

How to Cite

Wilkins, R. G. (1991) The Modification of Ligand Reactivity by Complex Formation, in Kinetics and Mechanism of Reactions of Transition Metal Complexes, 2nd Edition, Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim, FRG. doi: 10.1002/3527600825.ch6

Author Information

  1. University of Warwick, Dept. of Chemistry, Coventry CV4 7AL, Great Britain

Publication History

  1. Published Online: 2 JUN 2003
  2. Published Print: 27 AUG 1991

ISBN Information

Print ISBN: 9783527282531

Online ISBN: 9783527600823

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Keywords:

  • metal;
  • collecting point reactant;
  • reactant molecules;
  • metal-bound ligand;
  • hydrolysis;
  • carboxylate esters;
  • amides;
  • peptides;
  • nitriles;
  • phosphate esters;
  • coordinated ligands;
  • masking;
  • moleculare strain alternations

Summary

This chapter contains sections titled:

  • The Metal as a Collecting Point Reactant

    • Neighboring Group Effects

    • Template Chemistry

    • Collecting Reactant Molecules

  • Promotion of Reactions within the Metal-Bound Ligand

  • Hydrolysis of Coordinated Ligands

    • Carboxylate Esters: [BOND]CO2R [RIGHTWARDS ARROW] [BOND]CO2H

    • Amides and Peptides: [BOND]CONHR [RIGHTWARDS ARROW] [BOND]CO2H

    • Nitriles: [BOND]CN [RIGHTWARDS ARROW] [BOND]CONH2

    • Phosphate Esters: [BOND]ROPO32[BOND] [RIGHTWARDS ARROW] [BOND]PO43[BOND]

    • Other Groups

  • The Acidity of Coordinated Ligands

    • Coordinated Water

    • Coordinated Ammonia and Amines

    • Other Coordinated Ligands

  • Electrophilic Substitution in Metal Complexes

  • Masking Effects

  • Disturbance of Reaction Stoichiometry

  • Molecular Strain Alternations

  • Function of the Ligand

  • Conclusions