Standard Article
Denaturation of DNA
Nucleic Acids
Published Online: 15 SEP 2006
DOI: 10.1002/3527600906.mcb.200200014
Copyright © 2006 Wiley-VCH Verlag GmbH & Co. KGaA. All rights reserved.
Book Title
Reviews in Cell Biology and Molecular Medicine
Additional Information
How to Cite
Blake, R. D. 2006. Denaturation of DNA . Reviews in Cell Biology and Molecular Medicine. .
Publication History
- Published Online: 15 SEP 2006
- Abstract
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Abstract
Denatured DNA and RNA are disordered nonnative states brought about by any of the many means of disturbing noncovalent bonds supporting their native conformations: heat, nonaqueous denaturing solvents, low or high pHs, low ionic strengths. The denaturation process is generally reversible.
Keywords:
- Degradation;
- Stacking Forces;
- Melting Curve;
- TM ;
- Helix–Coil Transition
