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Bacterial Pathogenesis, Molecular Basis of

Molecular Biology of Specific Organisms

  1. Melanie Filiatrault,
  2. Luciano Passador

Published Online: 15 SEP 2006

DOI: 10.1002/3527600906.mcb.200300006

Reviews in Cell Biology and Molecular Medicine

Reviews in Cell Biology and Molecular Medicine

How to Cite

Filiatrault, M. and Passador, L. 2006. Bacterial Pathogenesis, Molecular Basis of. Reviews in Cell Biology and Molecular Medicine. .

Author Information

  1. University of Rochester Medical Center, Rochester, NY, USA

Publication History

  1. Published Online: 15 SEP 2006

Abstract

The incidence of infectious disease due to bacteria continues to be a leading cause of morbidity and mortality worldwide despite advances in public health measures, modern medicine, and the availability of myriad antimicrobial drugs. Those organisms that are able to cause disease are referred to as pathogens. These organisms have evolved many mechanisms to subvert the immune defenses of the human host and usurp usual host cell processes to allow their own proliferation and persistence during infections. In addition to uncovering the inner working of both bacterial and host cells, the elucidation of these processes provides the potential for the development of new therapeutic approaches.

Keywords:

  • Virulence;
  • Pathogen;
  • Adhesin;
  • Colonization;
  • Quorum sensing;
  • Antimicrobial Resistance;
  • Pathogenic Cycle