Standard Article
Biotransformations of Drugs and Chemicals
Pharmacology
Published Online: 15 SEP 2006
DOI: 10.1002/3527600906.mcb.200300009
Copyright © 2006 Wiley-VCH Verlag GmbH & Co. KGaA. All rights reserved.
Book Title
Reviews in Cell Biology and Molecular Medicine
Additional Information
How to Cite
Ortiz de Montellano, P. R. 2006. Biotransformations of Drugs and Chemicals. Reviews in Cell Biology and Molecular Medicine. .
Publication History
- Published Online: 15 SEP 2006
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Abstract
Drug and xenobiotic metabolism converts the lipophilic compounds that can be absorbed into the body into polar, excretable products, thus preventing their accumulation, but also sometimes forms more toxic products.
Keywords:
- Electrophilic;
- Endobiotic;
- LogP;
- Nucleophilic;
- Prodrug;
- Xenobiotic
