Published Online: 15 SEP 2006
Copyright © 2006 Wiley-VCH Verlag GmbH & Co. KGaA. All rights reserved.
Reviews in Cell Biology and Molecular Medicine
How to Cite
Burgoyne, R. D. and Morgan, A. 2006. Exocytosis. Reviews in Cell Biology and Molecular Medicine. .
- Published Online: 15 SEP 2006
Exocytosis is the process by which secretory vesicles fuse with the plasma membrane of cells to allow release of their contents and insertion of new membrane components. It is a mechanism that is essential for cell growth but also underlies the release of many different extracellularly-acting substances. All cells possess a pathway for constitutive exocytosis and many cell types also possess a pathway for regulated exocytosis that occurs only in response to an intracellular signal such as a rise in cytosolic calcium concentration. Regulated exocytosis is involved in the release of hormones and neurotransmitters and even in events involved in the fusion of the sperm and the egg. In all cases a common conserved machinery is resposible for membrane fusion during exocytosis.
- Ca2+ Sensor;
- Constitutive Exocytosis;
- Fusion Pore;
- Regulated Exocytosis;
- Secretory Vesicle;
- SNARE Proteins;
- Synaptic Vesicle