Standard Article

Gene Targeting

Biotechnology

  1. Michael M. Seidman1,
  2. John H. Wilson2

Published Online: 15 SEP 2006

DOI: 10.1002/3527600906.mcb.200300055

Reviews in Cell Biology and Molecular Medicine

Reviews in Cell Biology and Molecular Medicine

How to Cite

Seidman, M. M. and Wilson, J. H. 2006. Gene Targeting. Reviews in Cell Biology and Molecular Medicine. .

Author Information

  1. 1

    National Institute on Aging, NIH, Baltimore, MD, USA

  2. 2

    Baylor College of Medicine, Houston, TX, USA

Publication History

  1. Published Online: 15 SEP 2006

Abstract

The recognition and binding of a specific sequence in the chromosome of living cells by a reagent constructed for that application. The purpose may be sequence manipulation or modulation of transcription.

Keywords:

  • Gene Targeting;
  • Homologous Recombination;
  • Polyamide;
  • DNA Triple Helix;
  • Peptide Nucleic Acid (PNA)