Published Online: 15 SEP 2006
Copyright © 2006 Wiley-VCH Verlag GmbH & Co. KGaA. All rights reserved.
Reviews in Cell Biology and Molecular Medicine
How to Cite
Lutz, M. B., Berger, T., Schultz, E. and Steinkasserer, A. 2006. Dendritic Cells. Reviews in Cell Biology and Molecular Medicine. .
- Published Online: 15 SEP 2006
Dendritic cells (DC) are the most potent antigen-presenting cells known today. They are the only antigen-presenting cells able to induce naïve T helper and cytotoxic T cells and are thus also known as natures adjuvant. In this review article, we will cover several aspects regarding the biological function of DC including antigen processing and presentation as well as antigen delivery systems including viral and non-viral systems. Specific chapters will focus on the function of DC as immunostimulators and as inductors of tolerance. A specific section will describe the interaction between DC and viruses including viral escape strategies. The final chapter will focus on the use of modified DC vaccines in the fight against cancer and virus-associated malignancies.
- Clinical Studies;
- Dendritic Cells;
- Tumor Vaccine;