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Female Reproduction System, Molecular Biology of

Molecular Biology of Specific Organs or Systems

  1. Guck T. Ooi,
  2. Jock K. Findlay

Published Online: 15 SEP 2006

DOI: 10.1002/3527600906.mcb.200300159

Reviews in Cell Biology and Molecular Medicine

Reviews in Cell Biology and Molecular Medicine

How to Cite

Ooi, G. T. and Findlay, J. K. 2006. Female Reproduction System, Molecular Biology of. Reviews in Cell Biology and Molecular Medicine. .

Author Information

  1. Prince Henry's Institute of Medical Research, Victoria, Australia

Publication History

  1. Published Online: 15 SEP 2006

Abstract

The female reproductive system consists of the hypothalamus, pituitary, ovaries, breasts, and uterus. These organs make up a finely tuned system that controls puberty, the menstrual cycle, pregnancy and birth, lactation, and menopause. With the tools available through molecular biological approaches, we are able to come to a greater understanding of the complex interactions that operate in this system. The hormones, growth factors, and enzymes that are able to exert unique and specific effects in this system do so either locally or via endocrine mechanisms. The elucidation of the molecules involved in this regulation and their mechanisms of action leads to a better understanding of the physiology and pathophysiology of reproduction, and provides the potential means for developing better methods to control fertility and infertility.

Outlined below are some of the major hormonal regulatory systems that are important in the female reproductive processes.

Keywords:

  • Betaglycan;
  • BMPs;
  • Endocrine Regulation;
  • Endothelins;
  • Folliculogenesis;
  • FSH Isoforms;
  • G-Proteins;
  • Gonadotropin-releasing Hormone;
  • Gonadotropins;
  • GDF;
  • IGF;
  • IGFBP;
  • Leukemia Inhibitory Factor;
  • Local Regulation;
  • Oxytocin;
  • Receptors;
  • Second-messenger Systems;
  • Signal Transduction;
  • Steroidogenic Enzymes;
  • Tissue Remodeling Enzymes;
  • Transforming Growth Factor β-Superfamily;
  • Transmembrane Helices;
  • Zona Pellucida Proteins