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Cell Growth in Microgravity

Cell Biology

  1. Alamelu Sundaresan1,
  2. Diana Risin2,
  3. Neal R. Pellis2

Published Online: 15 SEP 2006

DOI: 10.1002/3527600906.mcb.200300183

Reviews in Cell Biology and Molecular Medicine

Reviews in Cell Biology and Molecular Medicine

How to Cite

Sundaresan, A., Risin, D. and Pellis, N. R. 2006. Cell Growth in Microgravity. Reviews in Cell Biology and Molecular Medicine. .

Author Information

  1. 1

    Universities Space Research Association (USRA), Division of Space and Life Sciences, Houston, Texas, USA

  2. 2

    NASA, Lyndon B. Johnson Space Center, Houston, Texas, USA

Publication History

  1. Published Online: 15 SEP 2006


Microgravity affects cells and tissues either through direct response elements within the cell or by influencing the environment in which the cell lives. Cells respond to decreased gravity and the reordering of forces by changes in gene expression and cellular function. This review will address the unique attributes of microgravity that influence cell growth and function, progressing from ground-based models of microgravity, the cellular response to microgravity, and experimental results from cell experiments in microgravity.


  • Microgravity;
  • Microgravity Analog Culture System (MACS);
  • Modeled Microgravity;
  • Three-dimensional Cell Growth;
  • T-cell Activation