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Stem Cells and Parkinson's Disease

  1. Emma Lane1,
  2. Maria Sundberg2,
  3. Jan Pruszak3

Published Online: 15 JUL 2012

DOI: 10.1002/3527600906.mcb.201100019

Encyclopedia of Molecular Cell Biology and Molecular Medicine

Encyclopedia of Molecular Cell Biology and Molecular Medicine

How to Cite

Lane, E., Sundberg, M. and Pruszak, J. 2012. Stem Cells and Parkinson's Disease. Encyclopedia of Molecular Cell Biology and Molecular Medicine. .

Author Information

  1. 1

    Welsh School of Pharmacy Pharmacology, Redwood Building, Cardiff, UK

  2. 2

    Harvard Medical School, Neuroregeneration Institute, McLean Hospital, Belmont, MA, USA

  3. 3

    University of Freiburg, Emmy Noether-Group for Stem Cell Biology, Institute of Anatomy & Cell Biology, Freiburg, Germany

Publication History

  1. Published Online: 15 JUL 2012

Abstract

In this chapter, novel cell therapeutic avenues for Parkinson's disease (PD) are summarized, and the requirements outlined to bring currently experimental approaches using neural cells generated from pluripotent stem cells to fruition. Specifically, universal principles, recent advancements and ongoing challenges in deriving and characterizing dopaminergic cell populations for successful transplantation in PD, are discussed.

Keywords:

  • Stem cells;
  • Parkinson's disease .;
  • Cell therapy;
  • Regenerative medicine;
  • Neural development