Induced Pluripotent Stem Cells
Published Online: 30 OCT 2012
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Reviews in Cell Biology and Molecular Medicine
How to Cite
Takahashi, K. and Yamanaka, S. 2012. Induced Pluripotent Stem Cells. Reviews in Cell Biology and Molecular Medicine. .
- Published Online: 30 OCT 2012
The fate of somatic cells can be converted to the pluripotent state by the combination of a few transcription factors. This technology is expected to overcome the issues of embryonic stem cells. In addition, such reprogrammed cells, when derived from genetic disorders, may contribute towards an understanding of pathogenesis. In this chapter, the past, present and future of reprogramming are introduced, together with details of induced pluripotent stem cells (iPSCs).