Developmental Cell Biology
Published Online: 15 MAR 2012
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Reviews in Cell Biology and Molecular Medicine
How to Cite
Dye, F. J. 2012. Developmental Cell Biology. Reviews in Cell Biology and Molecular Medicine. .
- Published Online: 15 MAR 2012
Developmental cell biology is concerned with the consequences of what cells do in the context of developing organisms. Developmental biologists are also concerned with events before fertilization, such as gametogenesis, and after birth (or its equivalent in nonmammalian species), such as metamorphosis and regeneration. The range of species in the purview of the developmental biologist covers, essentially, the entire living world–animals, plants, protists, fungi, and even prokaryotes. In the creation of a human being, cell proliferation is required to create the trillions of cells of which the body is composed; cell differentiation provides the more than 200 different types of cells identified to date in the human body; while morphogenesis shapes the body form that is characteristic of the human species. The present understanding of the molecular and cellular mechanisms that underlie these phenomena has progressed at an ever-increasing pace, and is testimony to the army of cell and developmental biologists worldwide. To understand the regulation of the cell cycle, apoptosis, cell differentiation, pattern formation, and cell movement (to mention only a few such phenomena), to understand the integration of their underlying molecular and cellular mechanisms, and to understand the developmental consequences of their operation, makes the early twenty-first century an exciting time to be a developmental cell biologist. It is also a hopeful time for those people suffering the ravages of dreadful diseases, such as cancer, and for those awaiting the promise of regenerative medicine.
- Cell cycle;
- Embryonic stem (ES) cells;
- Growth factors;
- Induced pluripotent stem cells (iPSCs);
- In-vitro fertilization (IVF);
- Intracellular signal transduction;
- microRNAs (miRNAs);
- Pluripotent cell;
- Stem cell;
- Transcription factors