Chapter 18. Nucleosomes and Anti-Nucleosome Autoantibodies as Mediators of Glomerular Pathology in Systemic Lupus Erythematosus

  1. Prof. Dr. Dr. Joachim R. Kalden2,
  2. Dr. Dr. Martin Herrmann3
  1. Jürgen W. C. Dieker,
  2. Johan van der Vlag,
  3. Jo H. M. Berden

Published Online: 16 SEP 2004

DOI: 10.1002/3527601457.ch18

Book Title

Apoptosis and Autoimmunity

Apoptosis and Autoimmunity

Additional Information

How to Cite

Dieker, J. W. C., van der Vlag, J. and Berden, J. H. M. (2004) Nucleosomes and Anti-Nucleosome Autoantibodies as Mediators of Glomerular Pathology in Systemic Lupus Erythematosus, in Apoptosis and Autoimmunity (eds J. R. Kalden and M. Herrmann), Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim, FRG. doi: 10.1002/3527601457.ch18

Editor Information

  1. 2

    University of Erlangen-Nuremberg, Department of Internal Medicine III and Institute for Clinical Immunology Krankenhausstraße 12 91054 Erlangen, Germany

  2. 3

    University of Erlangen-Nuremberg, Institute for Clinical Immunology Krankenhausstraße 12 91054 Erlangen, Germany

Author Information

  1. University of Nijmegen, Departments of Medicine, Division of Nephrology Intensive Care Medicine, PO Box 9101, 6500 HB Nijmegen, The Netherlands

Publication History

  1. Published Online: 16 SEP 2004
  2. Published Print: 1 DEC 2002

ISBN Information

Print ISBN: 9783527304424

Online ISBN: 9783527601455

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Keywords:

  • systemic lupus erythematosus;
  • nucleosomes;
  • anti-nucleosome autoantibodies;
  • glomerular pathology;
  • lupus nephritis

Summary

  • Introduction

  • Reactivity of Anti-Chromatin Antibodies with Glomerular Components

  • The Nucleosomes as Mediator of Autoantibody Binding to the GBM

  • Evidence for Nucleosome-Mediated Binding in Lupus Nephritis

  • Conclusion

  • References

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