Chapter 3. Anti-Inflammatory and Immunoregulatory Effects of Apoptotic Cells

  1. Prof. Dr. Dr. Joachim R. Kalden2,
  2. Dr. Dr. Martin Herrmann3
  1. Reinhard E. Voll1,
  2. Dr. Dr. Martin Herrmann3,
  3. Irute Girkontaite1,
  4. Christian Stach,
  5. Wasilis Kolowos1,
  6. Prof. Dr. Dr. Joachim R. Kalden2

Published Online: 16 SEP 2004

DOI: 10.1002/3527601457.ch3

Book Title

Apoptosis and Autoimmunity

Apoptosis and Autoimmunity

Additional Information

How to Cite

Voll, R. E., Herrmann, M., Girkontaite, I., Stach, C., Kolowos, W. and Kalden, J. R. (2004) Anti-Inflammatory and Immunoregulatory Effects of Apoptotic Cells, in Apoptosis and Autoimmunity (eds J. R. Kalden and M. Herrmann), Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim, FRG. doi: 10.1002/3527601457.ch3

Editor Information

  1. 2

    University of Erlangen-Nuremberg, Department of Internal Medicine III and Institute for Clinical Immunology Krankenhausstraße 12 91054 Erlangen, Germany

  2. 3

    University of Erlangen-Nuremberg, Institute for Clinical Immunology Krankenhausstraße 12 91054 Erlangen, Germany

Author Information

  1. 1

    Universität Erlangen-Nürnberg, Institut für Klinische Immunologie, Medizinische Klinik III, Krankenhausstraße 12, 91054 Erlangen, Germany

  2. 2

    University of Erlangen-Nuremberg, Department of Internal Medicine III and Institute for Clinical Immunology Krankenhausstraße 12 91054 Erlangen, Germany

  3. 3

    University of Erlangen-Nuremberg, Institute for Clinical Immunology Krankenhausstraße 12 91054 Erlangen, Germany

Publication History

  1. Published Online: 16 SEP 2004
  2. Published Print: 1 DEC 2002

ISBN Information

Print ISBN: 9783527304424

Online ISBN: 9783527601455

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CHAPTER TOOLS

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Keywords:

  • anti-inflammatory effects;
  • immunoregulation;
  • monocytes;
  • macrophages;
  • necrosis;
  • inflammation

Summary

  • Introduction

  • Anti-inflammatory Effects of Apoptotic Cells on Monocytes/Macrophages

  • The Role of Anti-inflammatory Cytokines for the Inhibition of Pro-inflammatory Cytokine Production

  • Monocyte/Macrophage Receptors receiving the Anti-inflammatory Signal from Apoptotic Cells

  • Intracellular Signaling Events Causing the Anti-inflammatory State in Macrophages

  • Apoptotic Cells Impair MHC Class II Surface Expression on Monocytes

  • Influence of Apoptotic Cells on DC Function in Allogeneic MLR

  • The Presence of Apoptotic Cells can Shift the Th Cell Response towards Th2

  • Apoptotic Cells Suppress Delayed-type Hypersensitivity (DTH) In Vivo

  • Necrosis and Inflammation

  • Implications of the Anti-inflammatory and Immunomodulatory Effects of Apoptotic Cells for Health and Disease

    • Apoptosis and Pregnancy

    • Apoptosis and Irradiation

    • Apoptosis and Cancer

    • Apoptosis and Infections

    • Apoptosis and Blood Transfusions

  • References

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