Chapter 8. Autoimmune Lymphoproliferative Syndromes (ALPS)

  1. Prof. Dr. Dr. Joachim R. Kalden2,
  2. Dr. Dr. Martin Herrmann3
  1. Frédéric Rieux-Laucat,
  2. Françoise Deist,
  3. Alain Fischer

Published Online: 16 SEP 2004

DOI: 10.1002/3527601457.ch8

Book Title

Apoptosis and Autoimmunity

Apoptosis and Autoimmunity

Additional Information

How to Cite

Rieux-Laucat, F., Deist, F. and Fischer, A. (2004) Autoimmune Lymphoproliferative Syndromes (ALPS), in Apoptosis and Autoimmunity (eds J. R. Kalden and M. Herrmann), Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim, FRG. doi: 10.1002/3527601457.ch8

Editor Information

  1. 2

    University of Erlangen-Nuremberg, Department of Internal Medicine III and Institute for Clinical Immunology Krankenhausstraße 12 91054 Erlangen, Germany

  2. 3

    University of Erlangen-Nuremberg, Institute for Clinical Immunology Krankenhausstraße 12 91054 Erlangen, Germany

Author Information

  1. INSERM Unit 429, Hopital Necker-Enfants Malades, 149 rue de Sevres, 75743 Paris Cedex 15, France

Publication History

  1. Published Online: 16 SEP 2004
  2. Published Print: 1 DEC 2002

ISBN Information

Print ISBN: 9783527304424

Online ISBN: 9783527601455

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CHAPTER TOOLS

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Keywords:

  • autoimmune lymphoproliferative syndromes (ALPS);
  • clinical presentation;
  • immunological data;
  • treatment

Summary

  • Introduction

  • Death Receptors and Signaling of Apoptosis

  • Clinical and Immunological Basis of ALPS

    • Definitions

    • Clinical Presentation

      • Lymphoproliferation

      • Autoimmune Manifestations

      • Other Clinical Manifestations

    • Laboratory Findings

      • Immunological Data

      • Pathological Findings

    • Treatment

  • Genetic and Molecular Bases of ALPS

    • ALPS 0

    • ALPS Ia

    • ALPS Ib

    • ALPS II

    • ALPS III

  • Mechanism of Autoimmunity in ALPS

  • Conclusion

  • References

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