Chapter 1. Five Not Four: History and Significance of the Fifth Base

  1. Dr. Stephan Beck1,
  2. Dr. Alexander Olek2
  1. Douglas S Millar,
  2. Robin Holliday,
  3. Geoffrey W Grigg

Published Online: 16 MAR 2005

DOI: 10.1002/3527601511.ch1

Book Title

The Epigenome: Molecular Hide and Seek

The Epigenome: Molecular Hide and Seek

Additional Information

How to Cite

Millar, D. S., Holliday, R. and Grigg, G. W. (2005) Five Not Four: History and Significance of the Fifth Base, in The Epigenome: Molecular Hide and Seek (eds S. Beck and A. Olek), Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim, FRG. doi: 10.1002/3527601511.ch1

Editor Information

  1. 1

    The Sanger Centre, Wellcome Trust Genome Campus, Hinxton, Cambridge CB 10 1SA, UK

  2. 2

    Epigenomics AG, Kastanienallee 24, 10435 Berlin, Germany

Publication History

  1. Published Online: 16 MAR 2005
  2. Published Print: 21 FEB 2003

ISBN Information

Print ISBN: 9783527304943

Online ISBN: 9783527601516

SEARCH

CHAPTER TOOLS

Get PDF (172K)

Keywords:

  • fifth base;
  • 5-methylcytosine;
  • genomic DNA;
  • gene silencing;
  • DNA methylation;
  • cancer cells;
  • nuclear transfer

Summary

This chapter contains sections titled:

  • Historical Introduction

  • Sequencing 5-methylcytosine (5-mC) Residues in Genomic DNA

  • Gene Silencing

  • Development

  • Abnormal DNA Methylation in Cancer Cells

  • Nuclear Transfer

  • Aging

  • The Future

Get PDF (172K)