Acknowledgments: Research in the author's laboratory over the past 30 years was supported at different times by the Deutsche Forschungsgemeinschaft, Bonn (SFB 74, SFB 274, Do-165-15, Do-165-17), the Bundesministerium für Bildung und Wissenschaft, the Thyssen Stiftung, Bonn, the Alexander von Humboldt Stiftung, Bonn, the Sander Stiftung, München, the Ministerium für Wissenschaft und Forschung des Landes Nordrhein-Westfalen, and the Bayerisches Staatsministerium für Landschaftsschutz und Umweltgestaltung.
Chapter 2. (Epi)genetic Signals: Towards a Human Genome Sequence of All Five Nucleotides
- Dr. Stephan Beck1,
- Dr. Alexander Olek2
Published Online: 16 MAR 2005
DOI: 10.1002/3527601511.ch2
Copyright © 2003 Wiley-VCH Verlag GmbH & Co. KGaA
Book Title
The Epigenome: Molecular Hide and Seek
Additional Information
How to Cite
Doerfler, W. (2005) (Epi)genetic Signals: Towards a Human Genome Sequence of All Five Nucleotides, in The Epigenome: Molecular Hide and Seek (eds S. Beck and A. Olek), Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim, FRG. doi: 10.1002/3527601511.ch2
Editor Information
- 1
The Sanger Centre, Wellcome Trust Genome Campus, Hinxton, Cambridge CB 10 1SA, UK
- 2
Epigenomics AG, Kastanienallee 24, 10435 Berlin, Germany
Publication History
- Published Online: 16 MAR 2005
- Published Print: 21 FEB 2003
ISBN Information
Print ISBN: 9783527304943
Online ISBN: 9783527601516
- Summary
- Chapter
Keywords:
- genetic signals;
- human genome sequence;
- nucleotides;
- DNA methylation;
- viral genomes;
- mammalian genomes;
- Ad12 genomes;
- hamster tumor cells;
- mouse genome;
- recombination
Summary
This chapter contains sections titled:
A Linguistic Prologue
Towards the Complete Sequence of the Human Genome with Five Nucleotides
Patterns of DNA Methylation – the Scaffold for Building a Functional Genome
DNA Methylation Patterns in Segments of the Human Genome and in Viral Genomes
On Viral Genomes and Foreign DNA Integrates
DNA Methylation Patterns in the Human Genome
Insertions of Foreign DNA into Established Mammalian Genomes
De Novo Methylation of Integrated Foreign DNA
Ad12 Genomes in Hamster Tumor Cells
De Novo Methylation of Foreign DNA Integrated into the Mouse Genome by Homologous or Heterologous Recombination
Genome-wide Perturbations in the Mammalian Genome upon Foreign DNA Insertion
Outlook and Recommendations