Chapter 4. Mammalian Epigenomics: Reprogramming the Genome for Development and Therapy

  1. Dr. Stephan Beck1,
  2. Dr. Alexander Olek2
  1. Wolf Reik,
  2. Wendy Dean

Published Online: 16 MAR 2005

DOI: 10.1002/3527601511.ch4

The Epigenome: Molecular Hide and Seek

The Epigenome: Molecular Hide and Seek

How to Cite

Reik, W. and Dean, W. (2005) Mammalian Epigenomics: Reprogramming the Genome for Development and Therapy, in The Epigenome: Molecular Hide and Seek (eds S. Beck and A. Olek), Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim, FRG. doi: 10.1002/3527601511.ch4

Editor Information

  1. 1

    The Sanger Centre, Wellcome Trust Genome Campus, Hinxton, Cambridge CB 10 1SA, UK

  2. 2

    Epigenomics AG, Kastanienallee 24, 10435 Berlin, Germany

Publication History

  1. Published Online: 16 MAR 2005
  2. Published Print: 21 FEB 2003

ISBN Information

Print ISBN: 9783527304943

Online ISBN: 9783527601516

SEARCH

Keywords:

  • mammalian epigenomics;
  • DNA methylation;
  • histone;
  • imprinting;
  • reprogramming;
  • cloning;
  • epimutations;
  • epigenetic inheritance

Summary

This chapter contains sections titled:

  • Introduction

  • DNA Methylation

  • Histone Modifications

  • Imprinting

  • Reprogramming and Cloning

  • Epimutations and Epigenetic Inheritance

  • Epigenomics: The Future

  • Conclusions