Chapter 6. Epigenetic Trouble: Human Diseases Caused by Epimutations

  1. Dr. Stephan Beck1 and
  2. Dr. Alexander Olek2
  1. Jörn Walter and
  2. Martina Paulsen

Published Online: 16 MAR 2005

DOI: 10.1002/3527601511.ch6

The Epigenome: Molecular Hide and Seek

The Epigenome: Molecular Hide and Seek

How to Cite

Walter, J. and Paulsen, M. (2003) Epigenetic Trouble: Human Diseases Caused by Epimutations, in The Epigenome: Molecular Hide and Seek (eds S. Beck and A. Olek), Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim, FRG. doi: 10.1002/3527601511.ch6

Editor Information

  1. 1

    The Sanger Centre, Wellcome Trust Genome Campus, Hinxton, Cambridge CB 10 1SA, UK

  2. 2

    Epigenomics AG, Kastanienallee 24, 10435 Berlin, Germany

Publication History

  1. Published Online: 16 MAR 2005
  2. Published Print: 21 FEB 2003

ISBN Information

Print ISBN: 9783527304943

Online ISBN: 9783527601516

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Keywords:

  • epigenetic trouble;
  • human diseases;
  • epimutations;
  • DNA methylation;
  • Rett syndrome;
  • ICF syndrome;
  • ATR-X syndrome;
  • fragile-X syndrome;
  • imprinting syndromes

Summary

This chapter contains sections titled:

  • Introduction

  • Mechanisms of DNA Methylation

  • Molecular Recognition of Methylation Patterns

  • Rett Syndrome

  • ICF Syndrome

  • ATR-X Syndrome

  • Fragile-X Syndrome

  • Imprinting Syndromes