Chapter 11. Chemoresistance in Cancer Cells

  1. Dr. Jean-Charles Sanchez,
  2. Dr. Garry L. Corthals,
  3. Prof. Dr. Denis F. Hochstrasser
  1. Dr. Julia Poland1,
  2. Prof. Dr. Dirk Schadendorf2,
  3. Dr. Hermann Lage3,
  4. Prof. Dr. Pranav Sinha1

Published Online: 20 SEP 2004

DOI: 10.1002/3527601562.ch11

Biomedical Applications of Proteomics

Biomedical Applications of Proteomics

How to Cite

Poland, J., Schadendorf, D., Lage, H. and Sinha, P. (2004) Chemoresistance in Cancer Cells, in Biomedical Applications of Proteomics (eds J.-C. Sanchez, G. L. Corthals and D. F. Hochstrasser), Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim, FRG. doi: 10.1002/3527601562.ch11

Editor Information

  1. Biomedical Proteomics Research Group, Laboratoire Central de Chimie Clinique, Hopitaux Universitaires de Genève, 24, rue Micheli-du-Crest, 1211 Genève 14, Switzerland

Author Information

  1. 1

    Institut für Medizinische und Chemische Labordiagnostik, LKH-Klagenfurt, St. Veiter Strasse 47A, 9020 Klagenfurt, Austria

  2. 2

    Klinische Kooperationseinheit für Dermatoonkologie (DKFZ), Universitäts-Hautklinik Mannheim, Theodor-Kutzer-Ufer 1, 68135 Mannheim, Germany

  3. 3

    Institut für Pathologie, Universitätsklinikum Charité Campus Charité-Mitte, Schumannstrasse 20–21, 10117 Berlin, Germany

Publication History

  1. Published Online: 20 SEP 2004
  2. Published Print: 27 JAN 2004

ISBN Information

Print ISBN: 9783527308071

Online ISBN: 9783527601561

SEARCH

Keywords:

  • cancer cells;
  • chemoresistance;
  • gastric cancer;
  • pancreatic cancer;
  • melanoma;
  • drug resistance

Summary

  • Introduction

  • Two-dimensional Electrophoresis Maps of Gastric Cancer, Pancreatic Cancer, and Melanoma

    • Gastric Cancer

    • Pancreatic Cancer

    • Melanoma

  • Evaluation of the 2-DE Protein Maps

    • Chemoresistance Overview

    • Mechanisms of Drug Resistance

    • Differentially Expressed Proteins in Drug-resistant Cancer Cells

  • Conclusions

  • References