Chapter 12. Diabetes Mellitus: Complex Molecular Alterations

  1. Dr. Jean-Charles Sanchez,
  2. Dr. Garry L. Corthals,
  3. Prof. Dr. Denis F. Hochstrasser
  1. Gerhard Schmid1,
  2. Dr. Jean-Charles Sanchez2

Published Online: 20 SEP 2004

DOI: 10.1002/3527601562.ch12

Book Title

Biomedical Applications of Proteomics

Biomedical Applications of Proteomics

Additional Information

How to Cite

Schmid, G. and Sanchez, J.-C. (2004) Diabetes Mellitus: Complex Molecular Alterations, in Biomedical Applications of Proteomics (eds J.-C. Sanchez, G. L. Corthals and D. F. Hochstrasser), Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim, FRG. doi: 10.1002/3527601562.ch12

Editor Information

  1. Biomedical Proteomics Research Group, Laboratoire Central de Chimie Clinique, Hopitaux Universitaires de Genève, 24, rue Micheli-du-Crest, 1211 Genève 14, Switzerland

Author Information

  1. 1

    Biomedical Proteomics Research Group, Central Clinical Chemistry Laboratory, Genève University Hospital, 24, rue Micheli-du-Crest, 1211 Genève 14, Switzerland

  2. 2

    Biomedical Proteomics Research Group, Laboratoire Central de Chimie Clinique, Hopitaux Universitaires de Genève, 24, rue Micheli-du-Crest, 1211 Genève 14, Switzerland

Publication History

  1. Published Online: 20 SEP 2004
  2. Published Print: 27 JAN 2004

ISBN Information

Print ISBN: 9783527308071

Online ISBN: 9783527601561

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Keywords:

  • diabetes mellitus;
  • molecular alterations;
  • pathogenesis of T1DM and T2DM;
  • proteomics approach

Summary

  • Introduction

    • Glucose Homeostasis

    • The Islets of Langerhans

    • The Pancreatic Beta-Cell

  • Molecular Alterations in the Pathogenesis of T1DM and T2DM

    • Type 1 Diabetes Mellitus

    • Type 2 Diabetes Mellitus

  • The Treatment of Diabetes Mellitus

  • Proteomics: a Global Approach to the Study of Diabetes Mellitus

    • Type 1 Diabetes Mellitus

    • Type 2 Diabetes Mellitus

  • Conclusions

  • References

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